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利用母亲营养指标(血红蛋白和总蛋白)对婴儿出生体重结果的影响,预测儿童非传染性疾病水平上升的范式转变。

Using the effects of maternal nutritional indicators (hemoglobin and total protein) on baby's birth weight outcome to forecast a paradigm shift toward increased levels of non-communicable diseases in children.

作者信息

Ahmadu Baba Usman, Yakubu Nyandaiti, Yusuph Haruna, Alfred Marshall, Bazza Buba, Lamurde Abdullahi Suleiman

机构信息

Department of Pediatrics, Federal Medical Center, Yola, Adamawa State, Nigeria.

出版信息

Ann Afr Med. 2013 Jan-Mar;12(1):29-33. doi: 10.4103/1596-3519.108247.

Abstract

BACKGROUND

Maternal malnutrition can lead to low birth weight in babies, which puts them at risk of developing non-communicable diseases later in life. Evidence from developed countries has shown that low birth weight is associated with a predisposition to higher rates of non-communicable diseases later in life. However, information on this is lacking in developing countries. Thus, this work studied the effects of maternal nutritional indicators (hemoglobin and total protein) on birth weight outcome of babies to forecast a paradigm shift toward increased levels of non-communicable diseases in children.

MATERIALS AND METHODS

Mother-baby pairs were enrolled in this study using systematic random sampling. Maternal haemogblobin and total proteins were measured using micro-hematocrit and biuret methods, and birth weights of their babies were estimated using the bassinet weighing scale.

RESULTS

Of the 168 (100%) babies that participated in this study, 122 (72.6%) were delivered at term and 142 (84.5%) had normal birth weights. Mean comparison of baby's birth weight and maternal hemoglobin was not significant (P = 0.483), that for maternal total protein was also not significant (P = 0.411). Even though positive correlation coefficients were observed between birth weight of babies, maternal hemoglobin and total proteins, these were however not significant.

CONCLUSION

Maternal nutrition did not contribute significantly to low birth weight in our babies. Therefore, association between maternal nutrition and low birth weight to predict future development of non-communicable diseases in our study group is highly unlikely. However, we recommend further work.

摘要

背景

孕产妇营养不良会导致婴儿出生体重偏低,这使他们在日后生活中面临患非传染性疾病的风险。发达国家的证据表明,低出生体重与日后生活中患非传染性疾病的较高倾向有关。然而,发展中国家缺乏这方面的信息。因此,本研究探讨了孕产妇营养指标(血红蛋白和总蛋白)对婴儿出生体重结果的影响,以预测儿童非传染性疾病水平上升的范式转变。

材料与方法

采用系统随机抽样法招募母婴对参与本研究。使用微量血细胞比容法和双缩脲法测量孕产妇血红蛋白和总蛋白,并使用摇篮秤估计其婴儿的出生体重。

结果

参与本研究的168名(100%)婴儿中,122名(72.6%)足月分娩,142名(84.5%)出生体重正常。婴儿出生体重与孕产妇血红蛋白的均值比较无显著差异(P = 0.483),孕产妇总蛋白的均值比较也无显著差异(P = 0.411)。尽管婴儿出生体重、孕产妇血红蛋白和总蛋白之间观察到正相关系数,但这些均无显著意义。

结论

孕产妇营养对我们研究中婴儿的低出生体重没有显著影响。因此,在我们的研究组中,孕产妇营养与低出生体重之间的关联以预测未来非传染性疾病的发展极不可能。然而,我们建议进一步开展研究。

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