Department of Ophthalmology, Yokohama City University Medical Center, Yokohama, Japan.
Retina. 2013 Apr;33(4):812-7. doi: 10.1097/IAE.0b013e3182807629.
To evaluate the difference in color contrast by performing a color contrast ratio (CR) analysis and resulting visibility of the internal limiting membrane (ILM) when stained with indocyanine green and brilliant blue G (BBG) during macular surgery by performing a color CR analysis.
The authors analyzed 40 consecutive cases in which vitrectomy with ILM removal was performed to treat a macular hole or an epiretinal membrane. The surgical procedure was performed in 21 patients (21 eyes) after staining with indocyanine green and in 19 patients (19 eyes) after staining with BBG. The color CRs were estimated based on digital analysis of the red, green, and blue data of the digital images captured, and the CRs obtained with the two dyes were compared.
Color contrast analysis was performed in all 40 eyes, in which the ILM was removed after staining with indocyanine green or BBG, and the CRs were estimated in every eye. The CR (mean ± SD) obtained with indocyanine green and BBG was 4.3 ± 0.3 and 2.4 ± 0.1, respectively. Indocyanine green provided a significantly higher CR than BBG (P = 0.015).
Digital color contrast analysis can be used to evaluate the visibility of digital images, and it may be useful when choosing the dye to use for staining the ILM better.
通过对吲哚菁绿（ICG）和亮蓝 G（BBG）染色后黄斑手术中内界膜（ILM）的色彩对比比分析（CR）和可视度进行评估。
作者分析了 40 例连续接受玻璃体切除术联合 ILM 切除治疗黄斑裂孔或视网膜前膜的患者。21 例患者（21 只眼）在 ICG 染色后，19 例患者（19 只眼）在 BBG 染色后进行手术。根据数字图像的红、绿、蓝数据的数字分析来估计色彩 CR，并比较两种染料获得的 CR。
对所有 40 只眼（在 ICG 或 BBG 染色后切除 ILM 后）进行了色彩对比分析，并对每只眼的 CR 进行了估计。ICG 和 BBG 的 CR（均值±标准差）分别为 4.3±0.3 和 2.4±0.1。ICG 提供的 CR 明显高于 BBG（P=0.015）。
数字色彩对比分析可用于评估数字图像的可视度，在选择 ILM 染色用染料时可能会有所帮助。
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