Atefi Najmosadat, Majedi Mehrdad, Peyghambari Shadi, Ghourchian Shadi
Assistant professor of dermatology, Rasoul-e-Akram Hospital, Tehran University of Medical Sciences, Tehran, Iran. Address: Rasoul-e-Akram Hospital, Tehran, Iran.
Med J Islam Repub Iran. 2012 Feb;26(1):22-6.
The relationship between Lichen Planus (LP) and diabetes was studied previously, but the results were in conflict. The aim of this study was to find the prevalence of diabetes mellitus (DM) in patients with LP among Iranian patients.
In this study, 80 patients with LP were enrolled. They referred to dermatology clinic of our hospital during one year. A self-designed checklist for the study included duration of the disease, the pattern of the distribution of lichenoid lesions and fasting blood sugar (FBS).
From 80 patients with LP, 16 (20%) had diabetes. Also, 14 patients (17.5%) had impaired fasting glucose. The mean age of diabetic patients was significantly higher than non-diabetic group (p=0.039). In addition, the duration of LP in patients with DM was significantly higher than non-diabetic patients (p=0.024).
In our study, we saw a high prevalence of DM among patients with LP. Comparing our findings with the overall prevalence of DM in Iran, there was a significant difference between the prevalence of DM among patients with LP and the overall prevalence (p=0.001). Regarding our findings screening for FBS in patients with LP is required in Iran.
此前已对扁平苔藓(LP)与糖尿病之间的关系进行了研究,但结果存在冲突。本研究的目的是确定伊朗患者中LP患者的糖尿病(DM)患病率。
本研究纳入了80例LP患者。他们在一年期间转诊至我院皮肤科门诊。本研究的一份自行设计的检查表包括疾病持续时间、苔藓样病变的分布模式和空腹血糖(FBS)。
80例LP患者中,16例(20%)患有糖尿病。此外,14例患者(17.5%)空腹血糖受损。糖尿病患者的平均年龄显著高于非糖尿病组(p=0.039)。此外,DM患者的LP病程显著长于非糖尿病患者(p=0.024)。
在我们的研究中,我们发现LP患者中DM的患病率很高。将我们的研究结果与伊朗DM的总体患病率进行比较,LP患者中DM的患病率与总体患病率之间存在显著差异(p=0.001)。基于我们的研究结果,伊朗需要对LP患者进行FBS筛查。