Prygiel Marta, Janaszek-Seydlitz Wiesława
Zakład Badania Surowic i Szczepionek Narodowego Instytutu Zdrowia Publicznego-Państwowego Zakładu Higieny w Warszawie .
Przegl Epidemiol. 2012;66(4):657-65.
Currently in the world there are two vaccines to protect against infection of human papilloma virus (HPV) which is the etiological agent of cervical cancer used since 2007. Evaluate the effectiveness of vaccines particularly the long-term immunity is still the subject of many trials. The review of many publications in order to compare and analyses the results of numerous studies on the efficacy and safety of vaccination against HPV was performed. Most studies have demonstrated the high effectiveness of vaccines in preventing invasine changes in the cervix that may lead to development of cancer among young women. Despite the decline the effectiveness of vaccines against HPV with age, the vaccines are effective in preventing of re-infection HPV in women after surgery associated with HPV infection. The data show also favorable safety of the HPV vaccines.
目前世界上有两种预防人乳头瘤病毒（HPV）感染的疫苗，自2007年起该病毒被视为宫颈癌的病原体。评估疫苗的有效性，尤其是长期免疫效果，仍是许多试验的主题。为比较和分析众多关于HPV疫苗接种效果和安全性的研究结果，对许多出版物进行了综述。大多数研究表明，疫苗在预防年轻女性宫颈侵袭性病变（可能导致癌症发生）方面具有高效性。尽管疫苗对HPV的预防效果会随年龄下降，但在预防HPV感染相关手术后女性再次感染HPV方面，这些疫苗是有效的。数据还显示HPV疫苗具有良好的安全性。
