[Efficacy and safety of vaccines against human papillomavirus (HPV)].

Currently in the world there are two vaccines to protect against infection of human papilloma virus (HPV) which is the etiological agent of cervical cancer used since 2007. Evaluate the effectiveness of vaccines particularly the long-term immunity is still the subject of many trials. The review of many publications in order to compare and analyses the results of numerous studies on the efficacy and safety of vaccination against HPV was performed. Most studies have demonstrated the high effectiveness of vaccines in preventing invasine changes in the cervix that may lead to development of cancer among young women. Despite the decline the effectiveness of vaccines against HPV with age, the vaccines are effective in preventing of re-infection HPV in women after surgery associated with HPV infection. The data show also favorable safety of the HPV vaccines.