Shimizu T, Nishimura T, Kaneko M, Morita T, Mizuno A, Sugiyama A
Dept. of Radiology, Hamamatsu Univ. School of Med.
Gan No Rinsho. 1990 May;36(6):719-27.
Metastatic tumors to the oral region are uncommon and most are located in the mandible, with only a few in the soft tissue of the oral cavity. A review of the literature has revealed only 63 cases of a gingival soft tissue metastases. The prevalent primary site are the lung, the liver and the kidney in that decreasing order. Reported are two lung carcinomas and an esophageal carcinoma all showing a metastases to the gingival soft tissue. The primary lesions of two lung carcinomas were diagnosed after the detection of the gingival lesions. In all cases the diseases had disseminated when the gingival metastases were diagnosed. The longest survival time was only 4 months. The prognosis for such cases is poor, but early diagnosis and treatment is essential in order to prevent the pain and discomfort associated with the ulceration, the infection, and the local tissue destruction by the lesions.
口腔区域的转移性肿瘤并不常见，大多数位于下颌骨，只有少数位于口腔软组织。文献回顾显示，仅有63例牙龈软组织转移的病例。常见的原发部位依次为肺、肝和肾。报道了两例肺癌和一例食管癌均出现牙龈软组织转移。两例肺癌的原发灶在牙龈病变被发现后才得以诊断。在所有病例中，当牙龈转移被诊断时，疾病已发生播散。最长生存期仅4个月。此类病例预后较差，但早期诊断和治疗对于预防与溃疡、感染以及病变导致的局部组织破坏相关的疼痛和不适至关重要。
