Piattelli A, Fioroni M, Rubini C
Oral Medicine and Pathology, Dental School, University of Chieti, Italy.
J Periodontol. 1999 Apr;70(4):441-4. doi: 10.1902/jop.1999.70.4.441.
Prostate cancer is the cause of 10% of cancer-related deaths in males in the United States. Metastases are found late in the course of the disease. Metastatic tumors of the oral cavity are rare, representing about 1% of oral tumors and affect jaws much more frequently than soft tissues. Metastatic prostate cancer tends to involve the bones of the axial skeleton. In a recent review, 22 cases of metastases to the jawbones from prostate cancer were found in 390 cases. On the other hand, only 1 case of a metastasis to the oral soft tissues was reported. The authors describe the second case of oral soft tissue metastasis from a prostate cancer. The metastatic lesion was located in the gingiva. Clinicians should be aware of oral soft tissue metastases since they can be the first sign of a not yet diagnosed malignant tumor and they can be very easily confused with several different benign lesions.
前列腺癌是美国男性癌症相关死亡原因的10%。转移通常在疾病晚期才被发现。口腔转移性肿瘤很罕见，约占口腔肿瘤的1%，且累及颌骨的频率远高于软组织。转移性前列腺癌往往累及中轴骨骼的骨头。在最近的一项综述中，390例病例中发现了22例前列腺癌转移至颌骨的情况。另一方面，仅报告了1例转移至口腔软组织的病例。作者描述了第二例前列腺癌口腔软组织转移的病例。转移病灶位于牙龈。临床医生应警惕口腔软组织转移，因为它们可能是尚未诊断出的恶性肿瘤的首发症状，且极易与几种不同的良性病变相混淆。
