Wu Y T
School of Stomatology, Beijing Medical University.
Zhonghua Kou Qiang Yi Xue Za Zhi. 1990 Sep;25(5):258-61, 317.
In a series of 2,409 oral and jaw malignant tumors, 25 are metastatic account for 1% of malignant tumors in these regions. The commonest sites of the primary tumors were uterus and thyroid (5 cases each), followed by lung and liver (4 cases each), breast and stomach (2 cases each), femur, kidney and esophagus (1 case each) Among 25 cases, 13 occurred in oral soft tissues (12 in gingiva and 1 lip) and 12 in the jaws Alterations in sensation of the lip was the commonest oral symptoms when the metastatic tumors occurred in the mandible. On the radiograms, osteolytic destruction (9/12) was more common than osteogenic (2/12) or cyst-like change (1/12). In the patients with metastatic tumor of oral soft tissues, the bone may be unchanged (4/10), or involved similar to those in carcinoma of gingiva (4/10) or periodontal diseases (2/10).
在一组2409例口腔颌面部恶性肿瘤中，有25例为转移性肿瘤，占这些部位恶性肿瘤的1%。原发肿瘤最常见的部位是子宫和甲状腺（各5例），其次是肺和肝（各4例）、乳腺和胃（各2例）、股骨、肾和食管（各1例）。在这25例中，13例发生于口腔软组织（12例在牙龈，1例在唇部），12例发生于颌骨。当转移性肿瘤发生在下颌骨时，唇部感觉改变是最常见的口腔症状。在X线片上，溶骨性破坏（9/12）比成骨性破坏（2/12）或囊肿样改变（1/12）更常见。在口腔软组织转移性肿瘤患者中，骨质可能无改变（4/10），或表现与牙龈癌（4/10）或牙周疾病（2/10）相似。
