Oral Health Research Institute, Department of Preventive and Community Dentistry, Indiana University School of Dentistry, Indianapolis, Ind. 46202-2876, USA.
Caries Res. 2013;47(4):325-9. doi: 10.1159/000347051. Epub 2013 Mar 7.
The interaction between stannous-containing dentifrice slurry and experimentally formed pellicles was investigated on enamel and root dentin using an erosion-remineralization-abrasion cycling model. The remineralizing solutions contained no proteins (negative control), mucin, casein, mucin + casein or albumin, for experimental pellicle formation. Toothbrushing was performed with fluoride toothpaste, with (TP + Sn) and without (TP) 3,500 ppm Sn. TP + Sn reduced surface loss for both enamel and root dentin (p < 0.05). The association between TP + Sn and albumin resulted in a significantly lower enamel surface loss (p < 0.05), suggesting positive interaction of stannous ion and albumin on dental erosion-abrasion protection. A similar trend was observed for root dentin, although less pronounced.
采用脱矿-再矿化-磨损循环模型,研究了含锡牙膏浆料与实验形成的牙菌斑之间的相互作用在牙釉质和根牙本质上的情况。再矿化溶液中不含蛋白质(阴性对照)、黏蛋白、酪蛋白、黏蛋白+酪蛋白或白蛋白,用于实验性牙菌斑形成。用含氟牙膏(TP+Sn)和不含氟牙膏(TP)刷牙,Sn 浓度为 3500ppm。TP+Sn 减少了牙釉质和根牙本质的表面损失(p<0.05)。TP+Sn 与白蛋白的结合导致牙釉质表面损失明显降低(p<0.05),表明锡离子与白蛋白在牙齿酸蚀磨损保护方面存在积极的相互作用。根牙本质也观察到类似的趋势,但不那么明显。