Staroverov I I, Tagieva I A, Pomerantsev E V, Ovasapian Iu A, Dorogun B N, Serov V P, Puchkov A T, Abramov S L, Plotnikov A N, Savchenko A P
Kardiologiia. 1990 Feb;30(2):49-53.
Thrombolytic therapy was performed in 59 patients within the first hours of myocardial infarction. Twenty three patients (Group 1) were given streptokinase (SK) by an emergency team, 36 patients (Group 2) received SK following coronary angiography. In Group 1, SK was initiated earlier (p less than 0.001) than in Group 2. In Group 1 there was no coronary artery occlusion in the appropriate site of myocardial infarction in 86% of the patients. In Group 2, coronary occlusion was detected in 88% reperfusion, in 50% of the cases. Severe overall and regional left ventricular contractility abnormalities were found within the first month of the disease. The incidence of complications is the same in the two groups. High efficiency and relatively safe of thrombolytic therapy in the prehospital period makes this method particularly promising for practical medicine.
59例心肌梗死患者在发病后的最初数小时内接受了溶栓治疗。23例患者（第1组）由急救小组给予链激酶（SK），36例患者（第2组）在冠状动脉造影后接受SK治疗。第1组开始使用SK的时间比第2组更早（p<0.001）。第1组中，86%的患者在心肌梗死的相应部位没有冠状动脉闭塞。在第2组中，88%的再灌注病例中检测到冠状动脉闭塞，50%的病例存在这种情况。在疾病的第一个月内发现了严重的整体和局部左心室收缩功能异常。两组并发症的发生率相同。院前溶栓治疗的高效性和相对安全性使得该方法在实际医学中特别有前景。
