The effects of whole-body vibration therapy on bone turnover, muscle strength, motor function, and spasticity in chronic stroke: a randomized controlled trial.

BACKGROUND

Whole-body vibration (WBV) has been used in older adults to improve bone health and neuromuscular function, and may have potential applications for stroke patients.

AIM

To investigate the effects of WBV on bone turnover, leg muscle strength, motor function, and spasticity among chronic stroke patients.

DESIGN

Randomized controlled trial (RCT).

SETTING

Community.

POPULATION

Eighty-two chronic stroke patients.

METHODS

The experimental group underwent exercise training with WBV stimulation for a maximum of 15 minutes, 3 days per week for 8 weeks. The controls received the same exercises without WBV. Participants were evaluated for isokinetic knee muscle strength, serum levels of bone formation and resorption markers, spasticity and motor function of the paretic leg at baseline, immediately after the 8-week training period, and 1-month follow-up.

RESULTS

Intention-to-treat analysis revealed no significant changes in levels of bone turnover markers and motor function of the paretic leg over time in both groups. Muscle strength outcomes showed no significant group×time interaction, with similar significant improvements found in both groups. Spasticity of the paretic knee was significantly reduced in the experimental group (P=0.005), but not in controls (P=0.465). No serious adverse events were reported.

CONCLUSION

The WBV protocol used in this study did not induce additional effects on bone turnover, knee muscle strength and paretic leg motor function among chronic stroke patients. WBV may have potential to modulate spasticity, but this requires further investigation.

CLINICAL REHABILITATION IMPACT

More study on WBV is required before it can be recommended as an adjunct treatment in rehabilitation of chronic stroke patients.