Lucke K, Strobel B, Foerster M, Laqua H
Klinik für Augenheilkunde der Medizinischen Universität zu Lübeck.
Klin Monbl Augenheilkd. 1990 Apr;196(4):205-9. doi: 10.1055/s-2008-1046155.
In spite of advances in surgical technique and the development of purified silicone oils, secondary glaucoma still develops in 10-20% of cases following silicone oil surgery. In the first part of this study it is shown by life-table analysis that factors such as early lens removal, inferior iridectomy, early silicone removal or the use of purified silicone oil have little or no influence on the development of glaucoma. In the second part an attempt is made to pinpoint possible causes of secondary glaucoma by re-examining all cases in which elevated intraocular pressure developed some time after silicone oil surgery. It was found that a multitude of factors (e.g., inflammation, angle-block, anterior peripheral synechiae and emulsification) were involved in the pathogenesis of temporary or persistent secondary glaucomas. In most cases pre-existing pathology was found to be responsible rather than the silicone oil itself. The majority of the cases in which the silicone oil caused secondary glaucoma by emulsification responded well to medication alone or removal of the silicone oil.
尽管手术技术有所进步且纯化硅油得到了发展，但在硅油手术后仍有10% - 20%的病例会发生继发性青光眼。在本研究的第一部分，通过寿命表分析表明，早期晶状体摘除、下方虹膜切除术、早期硅油取出或使用纯化硅油等因素对青光眼的发生影响很小或没有影响。在第二部分中，通过重新检查所有在硅油手术后一段时间出现眼压升高的病例，试图找出继发性青光眼的可能病因。研究发现，多种因素（如炎症、房角阻滞、周边前粘连和乳化）参与了暂时性或持续性继发性青光眼的发病机制。在大多数情况下，发现是先前存在的病变而非硅油本身导致了青光眼。大多数因乳化导致继发性青光眼的病例，单独用药或取出硅油后反应良好。
