Virginia Institute of Neuropsychiatry, Midlothian, VA, USA.
J Neuropsychiatry Clin Neurosci. 2013 Winter;25(1):32-9. doi: 10.1176/appi.neuropsych.11120377.
NeuroQuant® is a recently developed, FDA-approved software program for measuring brain MRI volume in clinical settings. The purpose of this study was to compare NeuroQuant with the radiologist's traditional approach, based on visual inspection, in 20 outpatients with mild or moderate traumatic brain injury (TBI). Each MRI was analyzed with NeuroQuant, and the resulting volumetric analyses were compared with the attending radiologist's interpretation. The radiologist's traditional approach found atrophy in 10.0% of patients; NeuroQuant found atrophy in 50.0% of patients. NeuroQuant was more sensitive for detecting brain atrophy than the traditional radiologist's approach.
NeuroQuant® 是一款最近开发的、获得 FDA 批准的软件程序,用于在临床环境下测量脑 MRI 容积。本研究的目的是在 20 名轻度或中度创伤性脑损伤(TBI)的门诊患者中,比较 NeuroQuant 与放射科医生基于视觉检查的传统方法。对每例 MRI 进行 NeuroQuant 分析,并将得出的容积分析与主治放射科医生的解读进行比较。放射科医生的传统方法发现 10.0%的患者有萎缩;NeuroQuant 发现 50.0%的患者有萎缩。NeuroQuant 比传统放射科医生的方法更敏感,能检测到脑萎缩。