Department of Clinical Epidemiology, Leibniz Institute for Prevention Research and Epidemiology - BIPS, Achterstraße 30, D - 28359 Bremen, Germany.
Europace. 2013 Oct;15(10):1436-44. doi: 10.1093/europace/eut048. Epub 2013 Mar 13.
Data on the epidemiology of atrial fibrillation (AF) and its antithrombotic management in elderly populations are scarce. The aims of this study were to estimate the incidence and prevalence of AF in the elderly in Germany and to describe antithrombotic management of AF cases.
Estimation of prevalence and incidence was based on data of three German statutory health insurances, which insured more than 800 000 people aged 65 years and older in the study period. The 1-year period prevalence of AF was estimated for each of the years 2004-2007. The incidence rate of AF in 2007 was assessed in patients with a preceding continuous 3-year insurance period without diagnoses of AF. Antithrombotic management of AF was described among incident AF cases in 2008 and predictors for lack of prescriptions of oral anticoagulants were identified. Age-standardized period prevalence of AF among those 65 years or older was 7.7% in 2004, 9.4% in 2005, 9.8% in 2006, and 10.3% in 2007. The age-standardized incidence of AF was 27.4 of 1000 person-years in 2007. Prevalence and incidence increased with age and were higher in men than in women. In 2008, 58.2% of new AF cases received antithrombotic drugs. Treatment was less common among women and older people.
Incidence and prevalence of AF are relatively high in the elderly in Germany. A considerable fraction of new AF cases did not receive antithrombotic drugs in routine care.
关于老年人心房颤动（AF）的流行病学及其抗血栓治疗的数据很少。本研究的目的是估计德国老年人中 AF 的发病率和患病率，并描述 AF 病例的抗血栓治疗情况。
根据三项德国法定健康保险的数据估计患病率和发病率，这些保险在研究期间为超过 800 000 名 65 岁及以上的人提供保险。估计了 2004 年至 2007 年每年的 1 年期间 AF 的患病率。在没有 AF 诊断的连续 3 年保险期之前的 2007 年评估 AF 的发病率。描述了 2008 年新发 AF 病例的抗血栓治疗情况，并确定了未开具口服抗凝剂处方的预测因素。2004 年、2005 年、2006 年和 2007 年，65 岁及以上人群中年龄标准化的 AF 患病率分别为 7.7%、9.4%、9.8%和 10.3%。2007 年的年龄标准化 AF 发病率为每 1000 人年 27.4 例。患病率和发病率随年龄增长而增加，男性高于女性。2008 年，58.2%的新发 AF 病例接受了抗血栓药物治疗。女性和老年人的治疗率较低。
德国老年人中 AF 的发病率和患病率相对较高。在常规护理中，相当一部分新发 AF 病例未接受抗血栓药物治疗。
