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胚胎性横纹肌肉瘤源于纵隔畸胎瘤:一个不常见的病例报告。

Embryonal rhabdomyosarcoma arising from a mediastinal teratoma: an unusual case report.

机构信息

Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

出版信息

J Korean Med Sci. 2013 Mar;28(3):476-9. doi: 10.3346/jkms.2013.28.3.476. Epub 2013 Mar 4.

Abstract

We report an unusual case of 9.5-cm-sized embryonal rhabdomyosarcoma arose from a mediastinal mature teratoma in a 46-yr-old man. A man presented with chest trauma as a result of an accident at 10 September 2011. On chest X-ray, an anterior mediastinal mass was detected. To obtain further information, chest computed tomography (CT) with contrast enhancement was performed, revealing an anterior mediastinal mass. Complete surgical excision was performed and entire specimen was evaluated. Pathologic diagnosis was embryonal rhabdomyosarcoma arising in mature cystic teratoma. After surgical excision, two cycles of dactinomycin-based chemotherapy were performed. Lung metastasis was detected on follow up CT in September 2012, and wedge resection was performed. Pathological finding of the lung lesion showed same feature with that of primary rhabdomyosarcoma.

摘要

我们报告了一例罕见的病例,一名 46 岁男性患者的纵隔成熟畸胎瘤中发生了 9.5 厘米大小的胚胎性横纹肌肉瘤。该患者于 2011 年 9 月 10 日因事故导致胸部外伤。胸部 X 线片显示前纵隔有一肿块。为了获取更多信息,进行了胸部 CT(增强)检查,显示前纵隔有一肿块。进行了完全的手术切除,并对整个标本进行了评估。病理诊断为成熟囊性畸胎瘤中发生的胚胎性横纹肌肉瘤。手术切除后,进行了两个周期的放线菌素 D 为基础的化疗。2012 年 9 月,在随访 CT 上发现了肺转移,并进行了楔形切除术。肺部病变的病理发现与原发性横纹肌肉瘤具有相同的特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/49be/3594615/781abe3690e8/jkms-28-476-g001.jpg

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