巨大未成熟纵隔畸胎瘤经化疗和手术切除治疗：病例报告。
A massive immature mediastinal teratoma treated with chemotherapy and surgical resection: a case report.
机构信息
Thoracic and Vascular Surgery Research Center, Shiraz University of Medical Science, Shiraz, Iran.
Students Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
J Cardiothorac Surg. 2023 Oct 16;18(1):294. doi: 10.1186/s13019-023-02389-w.
BACKGROUND
Teratoma is a type of germ cell tumor consisting of one or multiple tissues derived from germinal layers. The location and size of the tumor can cause various presentations. Here we report one of the largest ever cases of immature cystic teratoma.
CASE PRESENTATION
In this report, we presented a 24-year-old patient with dyspnea, chest pain, nausea, and anorexia. A computed tomography scan revealed a giant, right-sided mass measuring about 190 × 150 × 140 mm. Chemotherapy was initiated for the patient, followed by thoracotomy. Histopathological evaluation revealed the nature of the mass to be an immature mediastinal teratoma.
CONCLUSION
the incidence of immature mediastinal teratoma is uncommon, and due to its rarity, the diagnosis needs more profound evaluation studies such as radiological and pathological assessments. Immature teratomas are optimally treated by a combination of chemotherapy and complete resection.
背景
畸胎瘤是一种生殖细胞肿瘤，由来自生殖层的一种或多种组织组成。肿瘤的位置和大小可引起各种表现。这里我们报告了一例曾经最大的未成熟囊性畸胎瘤病例。
病例介绍
在本报告中，我们介绍了一位 24 岁的患者，其表现为呼吸困难、胸痛、恶心和厌食。计算机断层扫描显示一个巨大的右侧肿块，大小约为 190×150×140 毫米。患者接受了化疗，随后进行了开胸手术。组织病理学评估显示该肿块的性质为未成熟纵隔畸胎瘤。
结论
未成熟纵隔畸胎瘤的发病率并不常见，由于其罕见性，诊断需要更深入的评估研究，如影像学和病理学评估。未成熟畸胎瘤通过化疗和完全切除的联合治疗效果最佳。
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