Suppr超能文献

功能性不全的主干瓣膜修复术:早期和中期结果

Repair of incompetent truncal valves: early and mid-term results.

作者信息

Perri Gianluigi, Filippelli Sergio, Polito Angelo, Di Carlo Duccio, Albanese Sonia B, Carotti Adriano

机构信息

Unit of Cardiac Surgery, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.

出版信息

Interact Cardiovasc Thorac Surg. 2013 Jun;16(6):808-13. doi: 10.1093/icvts/ivt098. Epub 2013 Mar 13.

Abstract

OBJECTIVES

To analyse the factors associated with in-hospital mortality and mid-term significant neoaortic valve regurgitation (AR) after truncal valve (TV) repair.

METHODS

Eleven children underwent TV repair at our institution from July 1999 to March 2012. All children presented significant preoperative TV regurgitation. Valve anatomy was quadricuspid in 7 (64%) patients and tricuspid in 4 (36%). The median age and weight at surgery were 29.6 (range 0.3-173.2) months and 12 (range 2.2-49) kg, respectively. Repair included bicuspidalization through the approximation of two leaflets associated with triangular resection of the opposite one (n = 2, 18%), or either bicuspidalization or tricuspidalization of the TV through excision of one leaflet and related sinus of Valsalva (n = 9, 82%). In 3 patients, repair was associated with coronary detachment before cusp removal, followed by coronary reimplantation.

RESULTS

In-hospital death occurred in 2 (18%) patients. Factors associated with hospital mortality were age <1 year (P = 0.05), weight <3 kg (P = 0.02) and longer cross-clamping time (P = 0.008). Follow-up was complete for all patients [median follow-up time: 52.2 (range 132.2-2.5) months]. Mid-term significant AR occurred in 4 patients (45%, moderate in 2 and severe in 2). One with severe AR underwent successful valve replacement 4 months postoperatively, leading to freedom from reintervention of 91%. Freedom from significant AR was 76.2 (33.2-93.5) and 60.9 (20.2-85.6) at 1 and 2 years, respectively. There was a trend towards longer freedom from mid-term significant AR for patients who underwent cusp removal compared with those who did not (P = 0.07).

CONCLUSIONS

TV repair in children can be performed safely with fairly good and durable results. Cusp removal might decrease the rate of severe AR on mid-term follow-up.

摘要

目的

分析与法洛四联症(TV)修复术后院内死亡率及中期严重新主动脉瓣反流(AR)相关的因素。

方法

1999年7月至2012年3月,11例儿童在我院接受TV修复术。所有儿童术前均存在严重的TV反流。7例(64%)患者瓣膜解剖结构为四叶式,4例(36%)为三叶式。手术时的中位年龄和体重分别为29.6(范围0.3 - 173.2)个月和12(范围2.2 - 49)千克。修复方法包括通过将两个瓣叶靠拢并对相对的瓣叶进行三角形切除来形成双叶瓣(n = 2,18%),或通过切除一个瓣叶及相关的主动脉窦来对TV进行双叶瓣化或三叶瓣化(n = 9,82%)。3例患者在瓣叶切除前进行了冠状动脉游离,随后进行冠状动脉再植入。

结果

2例(18%)患者在院内死亡。与院内死亡率相关的因素为年龄<1岁(P = 0.05)、体重<3千克(P = 0.02)和较长的主动脉阻断时间(P = 0.008)。所有患者均完成随访[中位随访时间:52.2(范围132.2 - 2.5)个月]。4例患者(45%)出现中期严重AR,其中2例为中度,2例为重度。1例重度AR患者在术后4个月成功进行了瓣膜置换,免于再次干预的比例为91%。1年和2年时免于严重AR的比例分别为76.2(33.2 - 93.5)和60.9(20.2 - 85.6)。与未进行瓣叶切除的患者相比,进行瓣叶切除的患者中期免于严重AR的时间有延长趋势(P = 0.07)。

结论

儿童TV修复术可安全进行,效果良好且持久。瓣叶切除可能会降低中期随访时严重AR的发生率。

相似文献

1
Repair of incompetent truncal valves: early and mid-term results.功能性不全的主干瓣膜修复术:早期和中期结果
Interact Cardiovasc Thorac Surg. 2013 Jun;16(6):808-13. doi: 10.1093/icvts/ivt098. Epub 2013 Mar 13.
3
Fate of the truncal valve in truncus arteriosus.共同动脉干中动脉干瓣膜的转归
Ann Thorac Surg. 2008 Jan;85(1):172-8. doi: 10.1016/j.athoracsur.2007.07.039.
6
Long-term results of a strategy of aortic valve repair in the pediatric population.儿童人群主动脉瓣修复策略的长期结果。
J Thorac Cardiovasc Surg. 2013 Feb;145(2):461-7; discussion 467-9. doi: 10.1016/j.jtcvs.2012.11.033. Epub 2012 Dec 13.
8
Long-term follow-up of truncus arteriosus repaired in infancy: a twenty-year experience.婴儿期修复的永存动脉干的长期随访:二十年经验
J Thorac Cardiovasc Surg. 1997 May;113(5):869-78; discussion 878-9. doi: 10.1016/S0022-5223(97)70259-9.

本文引用的文献

1
Durability of truncal valve repair.干瓣修复的耐久性。
Ann Thorac Surg. 2010 Oct;90(4):1307-12; discussion 1312. doi: 10.1016/j.athoracsur.2010.06.018.
3
Techniques for repairing the aortic and truncal valves.主动脉瓣和肺动脉干瓣修复技术。
Cardiol Young. 2005 Feb;15 Suppl 1:125-31. doi: 10.1017/s1047951105001150.
8
Truncal valve repair: initial experience in neonates.躯干瓣膜修复:新生儿的初步经验。
Ann Thorac Surg. 1998 Jun;65(6):1737-40. doi: 10.1016/s0003-4975(98)00136-2.
9
Trends in the management of truncal valve insufficiency.躯干瓣膜功能不全的管理趋势。
Ann Thorac Surg. 1998 Feb;65(2):517-24. doi: 10.1016/s0003-4975(97)01064-3.
10
Doppler evaluation of aortic regurgitation in children.儿童主动脉瓣反流的多普勒评估
Am J Cardiol. 1997 Oct 1;80(7):927-31. doi: 10.1016/s0002-9149(97)00547-x.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验