Kolias Angelos G, Guilfoyle Mathew R, Helmy Adel, Allanson Judith, Hutchinson Peter J
Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK.
Pract Neurol. 2013 Aug;13(4):228-35. doi: 10.1136/practneurol-2012-000268. Epub 2013 Mar 13.
Traumatic brain injury (TBI) remains a major public health problem. This review aims to present the principles upon which modern TBI management should be based. The early management phase aims to achieve haemodynamic stability, limit secondary insults (eg hypotension, hypoxia), obtain accurate neurological assessment and appropriately select patients for further investigation. Since 2003, the mainstay of risk stratification in the UK emergency departments has been a system of triage based on clinical assessment, which then dictates the need for a CT scan of the head. For patients with acute subdural or extradural haematomas, time from clinical deterioration to operation should be kept to a minimum, as it can affect their outcome. In addition, it is increasingly recognised that patients with severe and moderate TBI should be managed in neuroscience centres, regardless of the need for neurosurgical intervention. The monitoring and treatment of raised intracranial pressure is paramount for maintaining cerebral blood supply and oxygen delivery in patients with severe TBI. Decompressive craniectomy and therapeutic hypothermia are the subject of ongoing international multi-centre randomised trials. TBI is associated with a number of complications, some of which require specialist referral. Patients with post-concussion syndrome can be helped by supportive management in the context of a multi-disciplinary neurotrauma clinic and by patient support groups. Specialist neurorehabilitation after TBI is important for improving outcome.
创伤性脑损伤(TBI)仍然是一个重大的公共卫生问题。本综述旨在阐述现代TBI管理应基于的原则。早期管理阶段旨在实现血流动力学稳定,限制继发性损伤(如低血压、缺氧),进行准确的神经学评估,并适当选择患者进行进一步检查。自2003年以来,英国急诊科风险分层的主要方法是基于临床评估的分诊系统,该系统决定了是否需要进行头部CT扫描。对于急性硬膜下或硬膜外血肿患者,从临床病情恶化到手术的时间应尽量缩短,因为这会影响其预后。此外,人们越来越认识到,重度和中度TBI患者应在神经科学中心接受治疗,无论是否需要神经外科干预。对于重度TBI患者,监测和治疗颅内压升高对于维持脑供血和氧输送至关重要。去骨瓣减压术和治疗性低温是正在进行的国际多中心随机试验的主题。TBI会引发多种并发症,其中一些需要专科转诊。脑震荡后综合征患者可以在多学科神经创伤诊所的支持性管理以及患者支持小组的帮助下得到改善。TBI后的专科神经康复对于改善预后很重要。