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评估轻度创伤性脑损伤管理的疗效。

Assessing the efficacy of mild traumatic brain injury management.

机构信息

Division of Neurosurgery, Southern Illinois University School of Medicine, Springfield, Illinois, United States.

Center for Clinical Research, Southern Illinois University School of Medicine, Springfield, Illinois, United States.

出版信息

Clin Neurol Neurosurg. 2021 Mar;202:106518. doi: 10.1016/j.clineuro.2021.106518. Epub 2021 Jan 27.

Abstract

OBJECTIVE

Intracranial hemorrhage (ICH) is frequently found on computed tomography (CT) after mild traumatic brain injury (mTBI) prompting transfer to centers with neurosurgical coverage and repeat imaging to confirm hemorrhage stability. Studies suggest routine repeat imaging has little utility in patients with minimal ICH, no anticoagulant/antiplatelet use, and no neurological decline. Additionally, it is unclear which mTBI patients benefit from transfer for neurosurgery consultation. The authors sought to assess the clinical utility and cost effectiveness of routine repeat head CTs and transfer to tertiary centers in patients with low-risk, mTBI.

METHODS

Retrospective evaluation of patients receiving a neurosurgical consultation for TBI during a 4-year period was performed at a level 1 trauma center. Patients were stratified according to risk for neurosurgical intervention based on their initial clinical evaluation and head CT. Only patients with low-risk, mTBI were included.

RESULTS

Of 531 patients, 119 met inclusion criteria. Eighty-eight (74.0 %) received two or more CTs. Direct cost of repeat imaging was $273,374. Thirty-seven (31.1 %) were transferred to our facility from hospitals without neurosurgical coverage, costing $61,384. No patient had neurosurgical intervention or mTBI-related in-hospital mortality despite enlarging ICH on repeat CT in three patients. Two patients had mTBI related 30-day readmission for seizure without ICH expansion.

CONCLUSION

Routine repeat head CT or transfer of low-risk, mTBI patients to a tertiary center did not result in neurosurgical intervention. Serial neurological examinations may be a safe, cost-effective alternative to repeat imaging for select mTBI patients. A large prospective analysis is warranted for further evaluation.

摘要

目的

轻度创伤性脑损伤(mTBI)后经常在计算机断层扫描(CT)上发现颅内出血(ICH),这促使患者转至具有神经外科覆盖的中心并进行重复成像以确认出血稳定性。研究表明,对于ICH 最小、无抗凝/抗血小板使用且无神经功能下降的患者,常规重复成像的实用性不大。此外,尚不清楚哪些 mTBI 患者从神经外科咨询中受益。作者旨在评估在低风险 mTBI 患者中常规重复头部 CT 和转至三级中心的临床实用性和成本效益。

方法

在一级创伤中心对 4 年内接受神经外科 TBI 咨询的患者进行回顾性评估。根据初始临床评估和头部 CT 将患者分为具有神经外科干预风险的分层。仅纳入低风险 mTBI 患者。

结果

在 531 名患者中,有 119 名符合纳入标准。88 名(74.0%)接受了两次或更多次 CT。重复成像的直接成本为 273,374 美元。37 名(31.1%)患者从没有神经外科覆盖的医院转至我院,花费 61,384 美元。尽管在三名患者中重复 CT 显示 ICH 扩大,但没有患者进行神经外科干预或 mTBI 相关院内死亡。两名患者因癫痫发作而在 mTBI 相关 30 天内再次入院,但 ICH 无扩大。

结论

常规重复头部 CT 或将低风险 mTBI 患者转至三级中心不会导致神经外科干预。对于某些 mTBI 患者,连续进行神经系统检查可能是一种安全、具有成本效益的替代重复成像的方法。需要进行大型前瞻性分析以进一步评估。

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