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德国北部石勒苏益格-荷尔斯泰因州口腔和咽癌的发病率及死亡率近期趋势

Recent trends in incidence and mortality of oral and pharyngeal cancer in Schleswig-Holstein in Northern Germany.

作者信息

Hertrampf K, Wiltfang J, Katalinic A, Timm O, Wenz H J

机构信息

Clinic of Oral and Maxillofacial Surgery, University Hospital of Schleswig-Holstein, Campus Kiel, Germany.

出版信息

Community Dent Health. 2012 Dec;29(4):268-73.

PMID:23488207
Abstract

OBJECTIVE

Oral and pharyngeal cancer is still a serious public health problem with more than 10,000 new cases every year in Germany, more than 4,000 patients die of this tumour each year. Aim of the project was a detailed analysis on incidence and mortality rates by age, gender and tumour sites in Northern Germany.

METHODS

The data on incidence and mortality rates from the population-based Cancer Registry of Schleswig-Holstein in Northern Germany were evaluated by age, gender and tumour sites from 2000 to 2006.

RESULTS

Some 3,127 new cases of oral and pharyngeal cancer (72% men, 28% women) were registered. About half of all cases were aged 60-79 years. The incidence trends for 40-59 years described a slight decrease. Trends for pharyngeal cancer showed the highest incidence rates for both genders in those aged 60-79. This detailed analysis with subgroups showed interesting differences and revealed considerable variations, especially compared to the increasing trends in several European countries.

CONCLUSIONS

These population-based data of Schleswig-Holstein showed interesting differences in the trends for incidence and mortality rates for age groups and tumour sites within the state and compared to the national German data and revealed noticeable different trends compared to several European countries. This population-based information informs effective cancer control.

摘要

目的

口腔和咽癌仍是一个严重的公共卫生问题,在德国每年有超过10000例新发病例,每年有超过4000名患者死于这种肿瘤。该项目的目的是对德国北部按年龄、性别和肿瘤部位划分的发病率和死亡率进行详细分析。

方法

对德国北部石勒苏益格-荷尔斯泰因州基于人群的癌症登记处2000年至2006年的发病率和死亡率数据按年龄、性别和肿瘤部位进行评估。

结果

登记了约3127例口腔和咽癌新病例(72%为男性,28%为女性)。所有病例中约一半年龄在60 - 79岁。40 - 59岁年龄组的发病率呈轻微下降趋势。咽癌的发病趋势显示,60 - 79岁人群中男女发病率均最高。这种按亚组进行的详细分析显示出有趣的差异,并揭示了相当大的变化,特别是与几个欧洲国家的上升趋势相比。

结论

石勒苏益格-荷尔斯泰因州这些基于人群的数据显示,该州内各年龄组和肿瘤部位的发病率和死亡率趋势存在有趣的差异,与德国全国数据相比也有明显不同趋势,与几个欧洲国家相比呈现出显著的不同趋势。这种基于人群的信息为有效的癌症控制提供了依据。

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引用本文的文献

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Oral cancer awareness campaign in Northern Germany: first positive trends in incidence and tumour stages.德国北部口腔癌宣传活动:发病率和肿瘤分期的初步积极趋势。
J Cancer Res Clin Oncol. 2020 Oct;146(10):2489-2496. doi: 10.1007/s00432-020-03305-8. Epub 2020 Jul 2.
2
Trends in incidence, tumour sites and tumour stages of oral and pharyngeal cancer in Northern Germany.德国北部口腔和咽癌的发病率、肿瘤部位和肿瘤分期趋势。
J Cancer Res Clin Oncol. 2012 Mar;138(3):431-7. doi: 10.1007/s00432-011-1118-6. Epub 2011 Dec 14.