Clinic of Oral and Maxillofacial Surgery, University Hospital of Schleswig-Holstein, Campus Kiel, Arnold-Heller Str.3, Haus 26, 24105 Kiel, Germany.
J Cancer Res Clin Oncol. 2012 Mar;138(3):431-7. doi: 10.1007/s00432-011-1118-6. Epub 2011 Dec 14.
Oral and pharyngeal cancer is the seventh leading tumour in Europe. In Germany, more than 10,000 new cancer cases are diagnosed each year. This population-based project evaluated the available data to develop a more detailed epidemiological profile of oral and pharyngeal cancer.
The data on incidence and mortality rates of the population-based Cancer Registry of Schleswig-Holstein were evaluated according to tumour sites, tumour stages and residential areas by age groups and gender from 2000 to 2006 and the tumour stages from 2000 to 2007.
From 2000 to 2006, 3,127 new cases of oral and pharyngeal cancer (72% in men vs. 28% in women) were registered. About 50% of all cases, in men and women, were between 60 and 79 years. This detailed analysis of tumour sites and tumour stages showed interesting differences and revealed considerable variations. The highest incidence rates for both men and women were diagnosed in stage IV for older people, in women for oral cancer and men for pharyngeal cancer. The highest incidence and mortality trends were observed in urban areas.
Detailed population-based results described important variations with regard to tumour sites, stages and areas. These data play a central role as they provide the epidemiological profile of a tumour. This profile, together with possible targeted knowledge evaluations of the public and the health care providers involved, can be used as a prerequisite for health care activities and for the development of preventive strategies for targeted public awareness campaigns.
口腔和咽癌是欧洲第七大常见肿瘤。在德国，每年诊断出超过 10000 例新癌症病例。本基于人群的项目评估了现有数据，以更详细地了解口腔和咽癌的流行病学特征。
根据肿瘤部位、肿瘤分期和年龄组及性别，对石勒苏益格-荷尔斯泰因癌症登记处的发病率和死亡率数据进行了评估，评估时间为 2000 年至 2006 年，并根据肿瘤分期评估了 2000 年至 2007 年的数据。
2000 年至 2006 年期间，共登记了 3127 例新的口腔和咽癌病例（男性占 72%，女性占 28%）。所有病例中约有 50%发生在 60 至 79 岁之间，男性和女性均如此。对肿瘤部位和肿瘤分期的详细分析显示出有趣的差异，并揭示了相当大的变化。对于老年人，男性和女性的所有病例中，IV 期的发病率最高，女性为口腔癌，男性为咽癌。在城市地区观察到发病率和死亡率的最高趋势。
基于人群的详细结果描述了肿瘤部位、分期和区域的重要变化。这些数据作为肿瘤的流行病学特征发挥着核心作用。该特征，结合对公众和相关医疗保健提供者的可能有针对性的知识评估，可以作为医疗保健活动的前提，并为有针对性的公众意识宣传活动制定预防策略。
