Surrey Memorial Hospital, Lower Mainland Pharmacy Services, British Columbia, Canada.
J Clin Pharm Ther. 2013 Jun;38(3):254-7. doi: 10.1111/jcpt.12053. Epub 2013 Mar 14.
Complementary medicines are commonly used by many patients. Caesium, a complementary therapy said to be of benefit for cancer treatment, has been associated with cardiac arrhythmias in the literature. We report a case of caesium-induced torsades de pointes and provide an evidence review.
A 46-year-old woman with syncope experienced torsades de pointes and cardiac arrest. Upon admission her QTc was 620 ms. The patient had taken caesium carbonate 10 g daily for 1 month prior to admission. The patient was successfully resuscitated and discharged home after 35 days in hospital.
Ten cases of caesium-induced cardiac arrhythmias have previously been reported in the literature. Treatment strategies differed significantly among the cases. However, all patients recovered from the event. Complementary and alternative medicines should not be overlooked as a potential cause of serious adverse events.
许多患者经常使用补充药物。在文献中，铯被称为对癌症治疗有益的补充疗法，但与心律失常有关。我们报告了一例铯引起的尖端扭转型室性心动过速，并进行了证据回顾。
一名 46 岁女性因晕厥出现尖端扭转型室性心动过速和心脏骤停。入院时，她的 QTc 为 620ms。该患者在入院前 1 个月每天服用碳酸铯 10g。患者成功复苏，在住院 35 天后出院回家。
文献中以前曾报道过 10 例铯引起的心律失常病例。这些病例的治疗策略有很大差异。然而，所有患者都从事件中恢复。补充和替代药物不应被忽视为严重不良事件的潜在原因。
