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血友病患者的踝关节融合术。

Ankle fusion in patients with haemophilia.

机构信息

UCLA/Orthopaedic Hospital Department of Orthopaedics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

出版信息

Haemophilia. 2013 May;19(3):432-7. doi: 10.1111/hae.12114. Epub 2013 Mar 13.

DOI:10.1111/hae.12114
PMID:23490189
Abstract

Ankle fusion in patients with haemophilia is a well-accepted treatment for end-stage arthropathy. However, current published outcome data are based on small sample sizes and generally short-term follow-up. The aim of this study was to evaluate the long-term results of ankle fusion in a large group of haemophilic patients treated at a single institution. The results of 57 ankle fusions performed on 45 patients between 1971 and 2010 were reviewed retrospectively. Data were gathered for type and severity of haemophilia, HIV status, fixation technique, postoperative complications and requirement of additional surgeries. A modified American Orthopaedic Foot & Ankle Society (AOFAS) hindfoot score was calculated for 20 ankles available for follow-up. Patients were followed for a mean of 6.6 years. There were no intra-operative or immediate postoperative complications related to fusion of the ankle. The overall non-union rate was 10.4% for tibio-talar fusion and 8.3% for sub-talar fusion. This rate was reduced to 3.7% and 5.6%, respectively, after the introduction of newer surgical techniques in 1995. None of these non-unions required revision surgery. The modified AOFAS scale demonstrated that 75% had no pain in the operated ankle a mean of 7.2 years following surgery. The remaining 25% scored their average pain as 3 of 10. The functional portion of the score suggested that patients have good alignment, minimal activity limitations or gait abnormalities, and can walk long distances. We conclude that ankle fusion successfully relieves pain and provides a good functional outcome. It is an appropriate treatment for end-stage haemophilic arthropathy of the ankle.

摘要

血友病患者的踝关节融合术是治疗终末期关节病的一种公认的治疗方法。然而,目前发表的结果数据基于小样本量,且通常为短期随访。本研究的目的是评估在一家机构接受治疗的大量血友病患者的踝关节融合术的长期结果。回顾性分析了 1971 年至 2010 年间对 45 例患者的 57 例踝关节融合术的结果。收集了血友病的类型和严重程度、HIV 状态、固定技术、术后并发症和需要额外手术的资料。对 20 例可随访的踝关节进行了改良美国矫形足踝协会(AOFAS)后足评分。患者平均随访 6.6 年。融合踝关节无手术相关或术后即刻并发症。总的骨不连率为距下融合 10.4%,跟距融合 8.3%。1995 年采用新的手术技术后,该比率分别降至 3.7%和 5.6%。这些骨不连均无需再次手术。改良 AOFAS 评分显示,75%的患者术后平均 7.2 年踝关节无痛,25%的患者平均疼痛评分为 3 分(满分 10 分)。评分的功能部分表明,患者具有良好的对线、最小的活动受限或步态异常,并且可以远距离行走。我们的结论是,踝关节融合术成功缓解了疼痛,并提供了良好的功能结果。它是治疗血友病终末期踝关节关节病的一种合适的治疗方法。

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