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踝关节融合术在血友病患者中的当前作用

The Current Role of Ankle Arthrodesis in Hemophilic Patients.

作者信息

Rodriguez-Merchan E Carlos

机构信息

Department of Orthopaedic Surgery, La Paz University Hospital-IdiPaz, Paseo de la Castellana 261, 28046-Madrid, Spain.

出版信息

Arch Bone Jt Surg. 2022 Feb;10(2):129-134. doi: 10.22038/abjs.2020.47865.2366.

DOI:10.22038/abjs.2020.47865.2366
PMID:35655735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9117902/
Abstract

There are several manners to take care of the hemophilic ankle in the initial phases of degeneration of the articular cartilage, in the event that hematologic prophylaxis is unsuccessful in accomplishing no bleeds. Some of these are nonoperative, with which management must start. These are Physical and Rehabilitation Medicine protocols and the utilization of orthoses (patellar tendon bearing). When these are unsuccessful, more aggressive types of treatment can be utilized, such as radiosynovectomy and some surgical operations (open or arthroscopic removal of anterior osteophyte of the distal part of the tibia, arthroscopic ankle debridement). Nonetheless, in the late phases of degeneration of the articular cartilage (advanced arthropathy), the solely options are surgical: ankle fusion or total ankle arthroplasty. The review of the literature has shown that the percentage of consolidation is between 90% and 100%, and that the percentage of postoperative infection is between 0% and 10%%. When the Ilizarov external fixator is utilized for ankle fusion, the percentage of pin tract infection is around 14%. Ankle fusion is a secure surgical technique that meliorates articular pain and improves the quality of life of hemophilic patients.

摘要

在关节软骨退变的初始阶段,如果血液学预防未能成功避免出血,有几种方法可以处理血友病性踝关节。其中一些是非手术方法,治疗必须从这些方法开始。这些方法包括物理和康复医学方案以及矫形器(髌腱承重)的使用。当这些方法不成功时,可以采用更积极的治疗方式,如放射性滑膜切除术和一些外科手术(开放或关节镜下切除胫骨远端前部骨赘、关节镜下踝关节清创术)。然而,在关节软骨退变的晚期(晚期关节病),唯一的选择是手术:踝关节融合或全踝关节置换。文献综述表明,融合成功率在90%至100%之间,术后感染率在0%至10%之间。当使用伊里扎洛夫外固定器进行踝关节融合时,针道感染率约为14%。踝关节融合是一种安全的外科技术,可减轻关节疼痛并改善血友病患者的生活质量。

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The Current Role of Ankle Arthrodesis in Hemophilic Patients.踝关节融合术在血友病患者中的当前作用
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Arch Bone Jt Surg. 2025;13(3):164-169. doi: 10.22038/ABJS.2024.80320.3667.

本文引用的文献

1
Ankle arthrodesis for end-stage haemophilic ankle arthropathy using a Ilizarov method.采用伊利扎洛夫(Ilizarov)方法治疗血友病性踝关节病终末期的踝关节融合术。
Int Orthop. 2020 May;44(5):995-1001. doi: 10.1007/s00264-020-04513-0. Epub 2020 Mar 3.
2
Risks and patient outcomes of surgical intervention for hemophilic arthropathy.血友病性关节病手术干预的风险和患者结局。
Expert Rev Hematol. 2019 May;12(5):325-333. doi: 10.1080/17474086.2019.1602035. Epub 2019 Apr 14.
3
Ankle fusion in hemophilic patients.
Orthop Traumatol Surg Res. 2017 Dec;103(8):1205-1209. doi: 10.1016/j.otsr.2017.08.016. Epub 2017 Sep 29.
4
Management of Hemophilic Arthropathy of the Ankle.踝关节血友病性关节病的管理
Cardiovasc Hematol Disord Drug Targets. 2017;17(2):111-118. doi: 10.2174/1871529X17666170908110758.
5
Long-term results of ankle arthrodesis in children and adolescents with haemophilia.血友病患儿及青少年踝关节融合术的长期疗效
Int Orthop. 2017 Aug;41(8):1579-1584. doi: 10.1007/s00264-017-3478-2. Epub 2017 Apr 20.
6
Hindfoot fusion in haemophilic arthropathy: 6-year mean follow-up of 41 procedures performed in 28 adult patients.血友病性关节病的后足融合术:对28例成年患者实施的41例手术的6年平均随访
Haemophilia. 2016 Mar;22(2):e87-e98. doi: 10.1111/hae.12863.
7
Total ankle replacement or ankle fusion in painful advanced hemophilic arthropathy of the ankle.晚期疼痛性踝关节血友病性关节炎的全踝关节置换或踝关节融合术。
Expert Rev Hematol. 2015 Dec;8(6):727-31. doi: 10.1586/17474086.2015.1087846. Epub 2015 Sep 10.
8
Functional outcomes following ankle arthrodesis in males with haemophilia: analyses using the CDC's Universal Data Collection surveillance project.血友病男性患者踝关节融合术后的功能结局:使用美国疾病控制与预防中心通用数据收集监测项目进行的分析
Haemophilia. 2014 Sep;20(5):709-15. doi: 10.1111/hae.12398. Epub 2014 Mar 16.
9
Arthroscopic ankle arthrodesis for end-stage haemophilic arthropathy of the ankle.
Haemophilia. 2014 Jan;20(1):e97-9. doi: 10.1111/hae.12308. Epub 2013 Nov 19.
10
Ankle fusion in patients with haemophilia.血友病患者的踝关节融合术。
Haemophilia. 2013 May;19(3):432-7. doi: 10.1111/hae.12114. Epub 2013 Mar 13.