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沙门氏菌产生的一种肠毒素的测定、表征及定位

Assay, characterization, and localization of an enterotoxin produced by Salmonella.

作者信息

Koupal L R, Deibel R H

出版信息

Infect Immun. 1975 Jan;11(1):14-22. doi: 10.1128/iai.11.1.14-22.1975.

DOI:10.1128/iai.11.1.14-22.1975
PMID:234910
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC415019/
Abstract

An enterotoxic factor isolated from cultures of Salmonella yielded reproducible results in the suckling mouse model in contrast to other animal models. The enterotoxin appears to possess properties similar to both the heat-stable and heat-labile enterotoxins of Escherichia coli. Preliminary results indicate that the toxin is a protein, is located in the cell wall or outer-membrane fraction, and is difficult to separate from other cell wall constituents.

摘要

与其他动物模型不同，从沙门氏菌培养物中分离出的一种肠毒素因子在乳鼠模型中产生了可重复的结果。该肠毒素似乎具有与大肠杆菌的耐热性和不耐热性肠毒素相似的特性。初步结果表明，该毒素是一种蛋白质，位于细胞壁或外膜部分，并且难以与其他细胞壁成分分离。

相似文献

1
Assay, characterization, and localization of an enterotoxin produced by Salmonella.沙门氏菌产生的一种肠毒素的测定、表征及定位
Infect Immun. 1975 Jan;11(1):14-22. doi: 10.1128/iai.11.1.14-22.1975.
2
Production, partial purification and characterization of Salmonella heat-labile enterotoxin.沙门氏菌不耐热肠毒素的制备、部分纯化及特性研究
Zentralbl Bakteriol Mikrobiol Hyg A. 1983 Nov;256(1):87-102.
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Cytoplasmic membrane vesicles of Escherichia coli. A simple method for preparing the cytoplasmic and outer membranes.大肠杆菌的细胞质膜囊泡。一种制备细胞质膜和外膜的简单方法。
J Biochem. 1975 Apr;77(4):705-18. doi: 10.1093/oxfordjournals.jbchem.a130774.
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Isolation of Salmonella wien heat-labile enterotoxin.维也纳沙门氏菌不耐热肠毒素的分离
Microbiologica. 1982 Jan;5(1):1-10.
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Immunogenicity and antigenic relationship of Salmonella enterotoxin with other enterotoxins.沙门氏菌肠毒素与其他肠毒素的免疫原性及抗原关系。
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[Production and purification of thermolabile enterotoxin of Escherichia coli (author's transl)].大肠杆菌不耐热肠毒素的生产与纯化（作者译）
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7
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Purification and chemical characterization of the heat-labile enterotoxin produced by enterotoxigenic Escherichia coli.产肠毒素大肠杆菌产生的不耐热肠毒素的纯化及化学特性分析
Infect Immun. 1979 Aug;25(2):586-96. doi: 10.1128/iai.25.2.586-596.1979.

引用本文的文献

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The pef fimbrial operon of Salmonella typhimurium mediates adhesion to murine small intestine and is necessary for fluid accumulation in the infant mouse.鼠伤寒沙门氏菌的菌毛操纵子介导对小鼠小肠的黏附，并且是幼鼠体内液体蓄积所必需的。
Infect Immun. 1996 Jan;64(1):61-8. doi: 10.1128/iai.64.1.61-68.1996.
2
The Salmonella dublin virulence plasmid mediates systemic but not enteric phases of salmonellosis in cattle.都柏林沙门氏菌毒力质粒介导牛沙门氏菌病的全身感染阶段，但不介导肠道感染阶段。
Infect Immun. 1995 Jul;63(7):2755-61. doi: 10.1128/iai.63.7.2755-2761.1995.
3
Alternate routes of invasion may affect pathogenesis of Salmonella typhimurium in swine.其他入侵途径可能会影响猪伤寒沙门氏菌的发病机制。
Infect Immun. 1995 Jul;63(7):2658-64. doi: 10.1128/iai.63.7.2658-2664.1995.
4
Cholera toxin-like toxin released by Salmonella species in the presence of mitomycin C.沙门氏菌在丝裂霉素C存在的情况下释放的霍乱毒素样毒素。
Infect Immun. 1980 Oct;30(1):224-30. doi: 10.1128/iai.30.1.224-230.1980.
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Effect of pH on the production of the Kanagawa hemolysin by Vibrio parahaemolyticus.pH对副溶血性弧菌产生神奈川溶血素的影响。
Infect Immun. 1981 Oct;34(1):115-9. doi: 10.1128/iai.34.1.115-119.1981.
6
Characterization of Salmonella toxin released by mitomycin C-treated cells.丝裂霉素C处理的细胞释放的沙门氏菌毒素的特性分析。
Infect Immun. 1981 May;32(2):916-26. doi: 10.1128/iai.32.2.916-926.1981.
7
Enterotoxigenicity and invasiveness of Salmonella species.
Antonie Van Leeuwenhoek. 1982;48(3):273-83. doi: 10.1007/BF00400387.
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Pathogenesis of experimental salmonellosis: inhibition of protein synthesis by cytotoxin.实验性沙门氏菌病的发病机制：细胞毒素对蛋白质合成的抑制作用。
Infect Immun. 1984 Jan;43(1):93-100. doi: 10.1128/iai.43.1.93-100.1984.
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Effect of lipopolysaccharide mutations on the pathogenesis of experimental Salmonella gastroenteritis.脂多糖突变对实验性沙门氏菌肠胃炎发病机制的影响。
Infect Immun. 1983 Apr;40(1):236-44. doi: 10.1128/iai.40.1.236-244.1983.
10
Pyridine nucleotide cycle of Salmonella typhimurium: in vitro demonstration of nicotinamide adenine dinucleotide glycohydrolase, nicotinamide mononucleotide glycohydrolase, and nicotinamide adenine dinucleotide pyrophosphatase activities.鼠伤寒沙门氏菌的吡啶核苷酸循环：烟酰胺腺嘌呤二核苷酸糖水解酶、烟酰胺单核苷酸糖水解酶和烟酰胺腺嘌呤二核苷酸焦磷酸酶活性的体外证明
J Bacteriol. 1981 Feb;145(2):1002-9. doi: 10.1128/jb.145.2.1002-1009.1981.

本文引用的文献

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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
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STUDIES ON THE GRAM-NEGATIVE CELL WALL. I. EVIDENCE FOR THE ROLE OF 2-KETO- 3-DEOXYOCTONATE IN THE LIPOPOLYSACCHARIDE OF SALMONELLA TYPHIMURIUM.革兰氏阴性菌细胞壁的研究。I. 2-酮-3-脱氧辛酸在鼠伤寒沙门氏菌脂多糖中作用的证据。
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Chemical and physical properties of cholera exo-enterotoxin (choleragen) and its spontaneously formed toxoid (choleragenoid).霍乱外毒素（霍乱原）及其自发形成的类毒素（类霍乱原）的化学和物理性质。
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Crystalline cholera toxin and toxoid.结晶霍乱毒素和类毒素。
Science. 1972 Feb 4;175(4021):529-30. doi: 10.1126/science.175.4021.529.
5
Pathogenesis of experimental cholera: biologic ativities of purified procholeragen A.实验性霍乱的发病机制：纯化前霍乱原A的生物学活性
J Immunol. 1966 Mar;96(3):440-9.
6
Enteropathogenicity of Escherichia coli. I. Evaluation of mouse intestinal loops.大肠杆菌的肠道致病性。I. 小鼠肠袢评估
Infect Immun. 1971 Oct;4(4):473-8. doi: 10.1128/iai.4.4.473-478.1971.
7
Enterotoxigenic Escherichia coli isolated from patients with severe cholera-like disease.从患有严重霍乱样疾病的患者中分离出的产肠毒素大肠杆菌。
J Infect Dis. 1971 Apr;123(4):378-85. doi: 10.1093/infdis/123.4.378.
8
Examination of the protein composition of the cell envelope of Escherichia coli by polyacrylamide gel electrophoresis.通过聚丙烯酰胺凝胶电泳对大肠杆菌细胞膜的蛋白质组成进行检测。
J Bacteriol. 1970 Nov;104(2):882-9. doi: 10.1128/jb.104.2.882-889.1970.
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The relationship between two apparently different enterotoxins produced by enteropathogenic strains of Escherichia coli of porcine origin.猪源致病性大肠杆菌产生的两种明显不同的肠毒素之间的关系。
J Med Microbiol. 1970 Aug;3(3):387-401. doi: 10.1099/00222615-3-3-387.
10
Response of the rabbit ileal loop to cell-free products from Escherichia coli enteropathogenic for swine.兔回肠袢对猪致病性大肠杆菌无细胞产物的反应。
J Infect Dis. 1970 Feb;121(2):182-7. doi: 10.1093/infdis/121.2.182.