Finkelstein R A, LoSpalluto J J
Science. 1972 Feb 4;175(4021):529-30. doi: 10.1126/science.175.4021.529.
The exo-enterotoxin of Vibrio cholerae has been obtained in crystalline form. A solution of the crystalline protein was equal in potency to the parent pure toxin in both choleragenicity and skin reactivity. Crystals of the natural toxoid, choleragenoid, resemble those of the toxin in appearance. A solution of crystalline choleragenoid was equivalent to the parent preparation in the flocculation test.
霍乱弧菌的外毒素已制成结晶形式。结晶蛋白溶液在致霍乱性和皮肤反应性方面的效力与母体纯毒素相当。天然类毒素霍乱类毒素的晶体在外观上与毒素晶体相似。结晶霍乱类毒素溶液在絮凝试验中与母体制剂相当。
