State Key Laboratory of Urban and Regional Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; Graduate University of Chinese Academy of Sciences, Beijing 100039, China.
Int J Hyg Environ Health. 2013 Nov;216(6):607-23. doi: 10.1016/j.ijheh.2013.02.002. Epub 2013 Mar 13.
This paper reviews recent studies on human exposure to polybrominated diphenyl ethers (PBDEs) in China, with particular focus on external exposure routes (e.g. diet and dust ingestion, inhalation of air) and internal doses based on biomonitoring studies of PBDEs (e.g. breast milk, blood and hair). PBDE concentrations reported for fish samples collected from electronic waste (e-waste) recycling sites, PBDE manufacturing sites, local markets in selected cities and estuarine areas in China have been compiled. House dust has been a significant contributor to human exposure to PBDEs in many countries. This is especially true for toddlers, who are exposed to significantly higher doses of PBDEs than adults. Infants are also exposed to high levels of PBDEs via breast-feeding. The general population's inhalation exposure to PBDEs from household products is likely a less significant source into the indoor environment. In addition, the contribution of several exposure pathways to PBDEs among various age groups was analyzed. We found that house dust contributed most to the daily exposure to PBDEs for both toddlers and adults in urban areas of China. Furthermore, workers and residents in and around electronic recycling and PBDE manufacturing sites are exposed to the highest PBDE levels among all populations studied thus far. For the occupationally exposed populations, BDE209 was the dominant congener, in most cases. Rigorous pollution prevention and occupational protection measures are needed in China to mitigate potential health effects associated with PBDE exposures.
本文综述了中国人体内多溴二苯醚(PBDEs)暴露的最新研究进展,重点关注了人体外部暴露途径(如饮食和灰尘摄入、空气吸入)和基于体内生物监测研究的内剂量(如母乳、血液和头发中的 PBDEs)。本文编译了从电子废物(电子垃圾)回收场、PBDE 制造场所、中国部分城市的当地市场和河口地区采集的鱼类样本中 PBDE 浓度的数据。在许多国家,房屋灰尘是人体暴露于 PBDEs 的主要来源。对于幼儿来说,这一点尤其如此,他们接触到的 PBDEs 剂量比成年人高得多。婴儿也通过母乳喂养接触到高水平的 PBDEs。一般人群通过家庭产品吸入 PBDEs 进入室内环境的暴露量可能较少。此外,本文还分析了不同年龄段人群通过各种暴露途径接触 PBDEs 的情况。我们发现,在中国城市地区,房屋灰尘对幼儿和成年人的每日 PBDEs 暴露量的贡献最大。此外,电子废物回收和 PBDE 制造场所及其周围的工人和居民暴露于所有研究人群中 PBDEs 水平最高。对于职业暴露人群,BDE209 是最主要的同系物,在大多数情况下都是如此。中国需要采取严格的污染预防和职业保护措施,以减轻与 PBDE 暴露相关的潜在健康影响。