Kidoh Masafumi, Nakaura Takeshi, Oda Seitaro, Namimoto Tomohiro, Awai Kazuo, Yoshinaka Ichiro, Harada Kazunori, Yamashita Yasuyuki
Diagnostic Radiology, Amakusa Medical Center, Kumamoto, Japan.
J Comput Assist Tomogr. 2013 Mar-Apr;37(2):159-64. doi: 10.1097/RCT.0b013e31827dbc08.
The objective of this study was to evaluate the effect of total body weight, height, body mass index, blood volume, lean body weight, and body surface area (BSA) on aortic and hepatic contrast enhancement during hepatic computed tomography (CT).
We calculated the changes in the CT number per gram of iodine ((Δ Hounsfield units/g [ΔHU/g])) for the aorta and the liver during portal venous phase. We performed linear regression analyses between ΔHU/g and each of the body parameters.
ΔHU/g and BSA showed the strongest inverse correlation. The correlation coefficients for the aorta and liver were 0.70 and 0.68 for ΔHU/g and total body weight, 0.41 and 0.37 for height, 0.54 and 0.55 for body mass index, 0.68 and 0.59 for blood volume, 0.70 and 0.62 for lean body weight, and 0.71 and 0.68 for BSA, respectively (P < 0.001 for all).
Our study supports the use of a protocol with iodine dose adjusted for the patient BSA.
本研究的目的是评估总体重、身高、体重指数、血容量、瘦体重和体表面积（BSA）对肝脏计算机断层扫描（CT）期间主动脉和肝脏对比增强的影响。
我们计算了门静脉期主动脉和肝脏每克碘的CT值变化（（Δ亨氏单位/克[ΔHU/g]））。我们对ΔHU/g与每个身体参数进行了线性回归分析。
ΔHU/g与BSA显示出最强的负相关。主动脉和肝脏的相关系数分别为：ΔHU/g与总体重为0.70和0.68，身高为0.41和0.37，体重指数为0.54和0.55，血容量为0.68和0.59，瘦体重为0.70和0.62，BSA为0.71和0.68（所有P<0.001）。
我们的研究支持使用根据患者BSA调整碘剂量的方案。
