Antoshchina M M, Luchnik N V
Radiobiologiia. 1990 Mar-Apr;30(2):261-3.
Chinese hamster cells with chromosomes differently substituted for BUdR (TT-TT, TT-TB, TB-TB, TB-BB, where T is thymidine containing chromatid and B is BUdR substituted chromatid) were exposed to UV-light in phase G2 and chromosome aberrations (mainly chromatid breaks) were analysed. Breaks frequency per chromosome was proportional to BUdR content. No breaks were found in TT-TT chromosomes. The frequency of breaks per TB chromatid was similar with TT-TB and TB-BB chromosomes. In TB-BB chromosomes, however, virtually no breaks occurred in TB chromatids whereas in BB chromatids, their frequency was much higher than was expected.
用不同的染色体被溴脱氧尿苷（BUdR）取代的中国仓鼠细胞（TT-TT、TT-TB、TB-TB、TB-BB，其中T是含胸腺嘧啶核苷的染色单体，B是被BUdR取代的染色单体）在G2期暴露于紫外线，并分析染色体畸变（主要是染色单体断裂）。每条染色体的断裂频率与BUdR含量成正比。在TT-TT染色体中未发现断裂。TB染色单体的断裂频率在TT-TB和TB-BB染色体中相似。然而，在TB-BB染色体中，TB染色单体几乎不发生断裂，而在BB染色单体中，其频率远高于预期。
