Filatov M V, Pantina R A, Frolova L I
Tsitologiia. 1986 Dec;28(12):1364-8.
The Chinese hamster cells V-79 were treated with BUdR during one cell cycle; after that the cells were grown in the medium without BUdR and were irradiated by longwave-UV-light at different time. The cell survival after photolysis was compared with the percentage of metaphase plates with different number of chromosomes containing BUdR. It is concluded that for cell inactivation the presence of only one destroyed chromosome (or its part) is enough.
中国仓鼠V-79细胞在一个细胞周期内用溴脱氧尿苷（BUdR）处理；之后，细胞在不含BUdR的培养基中培养，并在不同时间用长波紫外线照射。将光解后的细胞存活率与含有BUdR的不同染色体数目的中期板百分比进行比较。得出的结论是，对于细胞失活，仅存在一条受损染色体（或其部分）就足够了。
