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相对生存率与净生存率估计:进一步讨论的要点

Relative survival and the estimation of net survival: elements for further discussion.

作者信息

Estève J, Benhamou E, Croasdale M, Raymond L

机构信息

International Agency for Research on Cancer, Lyon, France.

出版信息

Stat Med. 1990 May;9(5):529-38. doi: 10.1002/sim.4780090506.

DOI:10.1002/sim.4780090506
PMID:2349404
Abstract

The methods of calculation of survival corrected for independent cause of death are discussed, and a maximum likelihood method is proposed and illustrated by survival of colon cancer patients in Geneva. The methods which are at present favoured for doing such calculations are subject to various biases when estimating net survival if the populations are heterogeneous for life expectancy. The proposed maximum likelihood approach would eliminate these biases by enabling relevant adjustment for covariates which influence survival. The routine use of such methods would permit better comparison of survival within and between populations.

摘要

讨论了针对独立死亡原因校正生存率的计算方法,并提出了一种最大似然法,并用日内瓦结肠癌患者的生存率进行了说明。如果人群的预期寿命存在异质性,目前用于进行此类计算的方法在估计净生存率时会受到各种偏差的影响。所提出的最大似然方法将通过对影响生存的协变量进行相关调整来消除这些偏差。常规使用此类方法将有助于更好地比较不同人群内部和之间的生存率。

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