乳腺癌放疗后放射性肺炎与机化性肺炎的关系。
Relationship between radiation pneumonitis and organizing pneumonia after radiotherapy for breast cancer.
机构信息
Department of Radiology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake, Toyoake, Aichi 470-1192, Japan.
出版信息
Radiat Oncol. 2013 Mar 8;8:56. doi: 10.1186/1748-717X-8-56.
BACKGROUND
Radiation pneumonitis (RP) and organizing pneumonia (OP) are the two main types of lung damage that can occur after lung irradiation. The goal of this study was to evaluate the relationship between RP and OP after irradiation for breast cancer.
METHODS
Four hundred and twenty-eight patients who underwent radiotherapy for breast cancer were identified. The whole breast was irradiated with two tangential photon beams. Chest computed tomography (CT) scan were performed when patients showed any symptoms that were suspicious for pneumonitis.
RESULTS
Five patients (1.2%) were diagnosed with OP. All five patients showed ground glass opacities and consolidation of the border of the lesion of RP in the radiation fields. Infiltration of OP spread from the site of RP to the hilum of the ipsilateral lung. Between RP and OP, a free region space (FRS) could be detected.
CONCLUSIONS
OP is closely related to RP. All OP lesions developed near the site of RP.
背景
放射性肺炎（RP）和机化性肺炎（OP）是肺部照射后可能发生的两种主要类型的肺损伤。本研究旨在评估乳腺癌放疗后 RP 和 OP 之间的关系。
方法
共确定了 428 例接受乳腺癌放疗的患者。采用两束切线光子束对全乳房进行照射。当患者出现疑似肺炎的症状时，进行胸部计算机断层扫描（CT）扫描。
结果
5 例（1.2%）患者被诊断为 OP。所有 5 例患者在 RP 照射野中均显示磨玻璃影和边界实变。OP 的浸润从 RP 部位向同侧肺门蔓延。在 RP 和 OP 之间，可以检测到自由区域空间（FRS）。
结论
OP 与 RP 密切相关。所有 OP 病变均发生在 RP 部位附近。
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