Institute of Biochemistry, Department of Biology, ETH Zurich, Schafmattstrasse 18, 8093 Zurich, Switzerland.
Cell. 2013 Mar 14;152(6):1222-5. doi: 10.1016/j.cell.2013.02.046.
During mitosis in vertebrate cells, the nuclear envelope undergoes extensive structural reorganization, starting with the retraction of nuclear membranes into the ER at mitotic onset and ending with the re-enclosure of chromatin by ER-derived membranes during mitotic exit. Here, we review our current understanding of postmitotic nuclear assembly.
在脊椎动物细胞的有丝分裂过程中,核膜经历广泛的结构重组,从有丝分裂开始时核膜向内质网回缩开始,到有丝分裂结束时由内质网衍生的膜重新包裹染色质结束。在这里,我们回顾了我们对有丝分裂后核组装的现有认识。