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国际协议研究:在不孕患者的门诊宫腔镜检查中诊断纵隔子宫。

The international agreement study on the diagnosis of the septate uterus at office hysteroscopy in infertile patients.

机构信息

Department of Reproductive Medicine and Gynecology, University Medical Center Utrecht, Utrecht, The Netherlands.

出版信息

Fertil Steril. 2013 Jun;99(7):2108-13.e2. doi: 10.1016/j.fertnstert.2013.02.027. Epub 2013 Mar 13.

DOI:10.1016/j.fertnstert.2013.02.027
PMID:23499151
Abstract

OBJECTIVE

To assess the international agreement on the hysteroscopic diagnosis of septate uterus.

DESIGN

Interobserver study.

SETTING

Eight hysteroscopy recordings were put online on the website of the European Society of Gynaecological Endoscopy.

PATIENT(S): Asymptomatic, infertile women indicated for a first in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) treatment cycle.

INTERVENTION(S): Office hysteroscopy.

MAIN OUTCOME MEASURE(S): The interobserver agreement on the uterine shape and necessity to correct the abnormality found.

RESULT(S): Seventy-eight observers from 24 different countries assessed 8 hysteroscopy recordings. The interobserver agreement on uterine shape variations septate and arcuate was fair (intraclass correlation coefficient = 0.27). Observers from the same country reached a significantly higher level of agreement. The agreement on the necessity of correction was poor (intraclass correlation coefficient = 0.17). The most distinct features for diagnosing a septate uterus judged to be the extent of endocavitary bulging and the angle of the bulging structure from the fundal area.

CONCLUSION(S): The agreement among international experts on the hysteroscopic diagnosis of the septate uterus was found to be poor. This may have implications for the accuracy of screening hysteroscopy for diagnosing uterine cavity abnormalities in infertile patients. Development of consented definitions for the hysteroscopic diagnosis of septate and arcuate uterus is recommended.

摘要

目的

评估宫腔镜诊断纵隔子宫的国际共识。

设计

观察者间研究。

地点

在欧洲妇科内镜学会的网站上在线发布了 8 个宫腔镜录像。

患者

无症状、不孕,拟行首次体外受精(IVF)/卵胞浆内单精子注射(ICSI)治疗周期的妇女。

干预措施

门诊宫腔镜检查。

主要观察指标

观察者间对子宫形状和发现的异常是否需要矫正的一致性。

结果

来自 24 个不同国家的 78 名观察者评估了 8 个宫腔镜录像。对纵隔子宫和弓形子宫的子宫形状变化的观察者间一致性为中等(组内相关系数=0.27)。来自同一国家的观察者达成了更高水平的一致性。对异常矫正必要性的一致性较差(组内相关系数=0.17)。诊断纵隔子宫最明显的特征是宫腔内膨出的程度和膨出结构与宫底区域的角度。

结论

国际专家对宫腔镜诊断纵隔子宫的一致性较差。这可能会影响到筛查宫腔镜诊断不孕患者宫腔异常的准确性。建议对宫腔镜诊断纵隔和弓形子宫达成一致的定义。

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