Webb A R, Pilbeam C, Hanafin N, Holick M F
Vitamin D, Skin and Bone Research Laboratory, Boston University School of Medicine, MA 02118.
Am J Clin Nutr. 1990 Jun;51(6):1075-81. doi: 10.1093/ajcn/51.6.1075.
We investigated the vitamin D status of a Caucasian elderly population in a long-term-care facility in Boston. Comparison was made with a group of free-living elderly people. The sunlight exposure of residents was monitored and its effect on the serum concentrations of 25-hydroxyvitamin D [25(OH)D] was compared with contributions from diet and multivitamins. Seasonal changes in serum 25(OH)D concentrations caused by sunlight exposure were greatest in the free-living subjects and declined in magnitude as the mobility of the volunteers decreased. Diet failed to provide an adequate amount of vitamin D for volunteers who had minimal outdoor activity. Use of a multivitamin supplement containing 10 micrograms (400 IU) vitamin D maintained serum 25(OH)D concentrations greater than 37.5 nmol/L.
我们调查了波士顿一家长期护理机构中白种老年人群的维生素D状况。并与一组自由生活的老年人进行了比较。监测了居民的阳光照射情况,并将其对血清25-羟基维生素D [25(OH)D]浓度的影响与饮食和复合维生素的作用进行了比较。阳光照射引起的血清25(OH)D浓度的季节性变化在自由生活的受试者中最大,并且随着志愿者活动能力的下降而减小。对于户外活动极少的志愿者,饮食无法提供足够量的维生素D。使用含有10微克(400国际单位)维生素D的复合维生素补充剂可使血清25(OH)D浓度维持在大于37.5纳摩尔/升。