Sem S W, Sjøen R J, Trygg K, Pedersen J I
Institute of Nutrition Research, University of Oslo, Norway.
Compr Gerontol A. 1987 Sep;1(3):126-30.
Vitamin D status of two groups of elderly was determined by measuring serum concentrations of 25-hydroxyvitamin D3 (25-OHD), and dietary and supplemental vitamin D intake. Group A consisted of 35 women (mean age 86 years), and 21 men (mean age 80 years) living in 5 different homes for elderly. Group B consisted of free-living elderly, 24 women (mean age 76 years) and 7 men (mean age 79 years). There was no or little seasonal variation in serum 25-OHD concentrations in either group. Of those who did not use vitamin D supplements, 83% of the women and 77% of the men in group A, and 40% of the women and none of the men in group B had 25-OHD concentrations below 20 ng/ml in the winter serum samples. Of the 49 individuals who used supplements, only 2 had values below 20 ng/ml. In the institutionalized elderly, 14-15 micrograms vitamin D per day as supplement was associated with a mean increase in 25-OHD concentration in winter serum samples of 25 ng/ml. Dietary intakes of vitamin D were low for both groups, especially for the women (less than 3 micrograms). It is concluded that elderly Norwegians, in particular those living in institutions, ought to improve their vitamin D status by increasing their exposure to sunshine and by including more oily fish in their diet. If this is difficult to achieve, vitamin D supplement (10 micrograms/day) should be used.
通过测量血清25-羟维生素D3(25-OHD)浓度以及饮食和补充维生素D的摄入量,来确定两组老年人的维生素D状况。A组由居住在5个不同养老院的35名女性(平均年龄86岁)和21名男性(平均年龄80岁)组成。B组由独立生活的老年人组成,包括24名女性(平均年龄76岁)和7名男性(平均年龄79岁)。两组的血清25-OHD浓度均无季节性变化或变化很小。在未使用维生素D补充剂的人群中,A组83%的女性和77%的男性,以及B组40%的女性和所有男性在冬季血清样本中的25-OHD浓度低于20 ng/ml。在49名使用补充剂的个体中,只有2人的数值低于20 ng/ml。在机构养老的老年人中,每天补充14 - 15微克维生素D与冬季血清样本中25-OHD浓度平均升高25 ng/ml相关。两组的维生素D饮食摄入量都很低,尤其是女性(低于3微克)。研究得出结论,挪威老年人,尤其是那些住在养老院的老人,应该通过增加日照时间和在饮食中增加更多油性鱼类来改善他们的维生素D状况。如果难以做到这一点,应使用维生素D补充剂(每天10微克)。