Department of Microbiology, School of Medicine & Infectious and Tropical Diseases Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Burns. 2013 Jun;39(4):650-4. doi: 10.1016/j.burns.2013.02.005. Epub 2013 Mar 15.
The rate of the MRSA strains, particularly at burn centers, is increasing worldwide. Detection of mupirocin resistance MRSA strains in the burn centers particularly from personnel will help to control these strains. For this purpose, a total of 116 Staphylococcus aureus isolates from the patients (burns) and personnel (nostrils) in Ahvaz Taleghani hospital (Iran) were investigated. The methicillin and mupirocin resistant isolates were detected by multiplex amplification of the mecA and ileS-2 genes. The mecA was found among 80% of isolates. The rates of mupirocin resistant strains among personnel and patients were 70% and 6%, respectively. The carriage rates of the S. aureus, MRSA and MRSA with high-level mupirocin resistance in the personnel were 40%, 34% and 28%, respectively. In conclusions, the high prevalence of MRSA strains in the patients showed the potential outbreak of the MRSA in the burn center and highlighted the need of antibiotic susceptibility monitoring of MRSA. Moreover being personnel as a main reservoir in terms of MRSA strains with high-level mupirocin resistance emphasizes the screening of the personnel in terms of the MRSA in the healthcare system especially in the burn center.
耐甲氧西林金黄色葡萄球菌（MRSA）菌株的发生率在全球范围内不断上升，尤其是在烧伤中心。检测烧伤中心工作人员和患者携带的耐莫匹罗星 MRSA 菌株有助于控制这些菌株。为此，对伊朗阿瓦士 Taleghani 医院的 116 例患者（烧伤）和工作人员（鼻腔）分离的金黄色葡萄球菌进行了研究。采用 mecA 和 ileS-2 基因多重扩增法检测耐甲氧西林和耐莫匹罗星的金黄色葡萄球菌。80%的分离株中存在 mecA 基因。工作人员和患者中耐莫匹罗星的金黄色葡萄球菌的发生率分别为 70%和 6%。工作人员中金黄色葡萄球菌、MRSA 和高水平耐莫匹罗星的 MRSA 的携带率分别为 40%、34%和 28%。总之，患者中 MRSA 菌株的高流行率表明烧伤中心可能爆发了 MRSA，这突出了监测 MRSA 对抗生素敏感性的必要性。此外，由于工作人员是高水平耐莫匹罗星的 MRSA 菌株的主要储存库，因此强调了在医疗保健系统中对工作人员进行 MRSA 筛查，尤其是在烧伤中心。
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