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[人工血液循环心脏手术后的多器官功能衰竭综合征]

[The multiple organ failure syndrome after cardiac surgery with artificial blood circulation].

作者信息

Babaev M A, Eremenko A A, Minbolatova N M, Dzemeshkevich S L

出版信息

Khirurgiia (Mosk). 2013(2):119-23.

Abstract

The 10-year study of etiology, pathogenesis, diagnostic, treatment and prevention of the multiple organ failure syndrome (MOFS) after cardiovascular operations with artificial blood circulation was conducted in the SCS. 4383 patients, aged 16-75 years, were observed. Of them, MOFS was diagnosed in 206 (4.7%) patients. Extracorporal detoxication was used in 385 patients. When used in patients with complicated postoperative period, the extracorporal detoxication prevents MOFS and decreases lethality in 3 times (from 59.3 to 19.2%). The method is indicated to patients with MOFS severity estimated of 13.5 points and damage of 5-6 organ systems. Herewith the duration of veno-venous ultrahemodiafiltration should not exceed 80 hours and the number of sessions should not be more then 3.

摘要

在心血管外科中心对人工血液循环心血管手术后多器官功能衰竭综合征(MOFS)的病因、发病机制、诊断、治疗及预防进行了为期10年的研究。观察了4383例年龄在16至75岁的患者。其中,206例(4.7%)患者被诊断为MOFS。385例患者采用了体外解毒疗法。当用于术后病情复杂的患者时,体外解毒可预防MOFS,并将死亡率降低3倍(从59.3%降至19.2%)。该方法适用于MOFS严重程度估计为13.5分且5至6个器官系统受损的患者。静脉-静脉超滤血液滤过的持续时间不应超过80小时,治疗次数不应超过3次。

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