The Department of Orthopaedic Surgery, Copenhagen University Hospital of Hvidovre, Kettegaards Allé 30, 2650 Hvidovre, Denmark.
Eur Spine J. 2013 Aug;22(8):1907-12. doi: 10.1007/s00586-013-2735-3. Epub 2013 Mar 16.
Schmorl's nodes (SNs) are commonly seen in vertebral imaging of the normal adult population referred for different reasons and are duly noted by the radiologist. However, little is known about their etiology: either SNs are perceived as largely inert developmental or congenital herniations of disc tissue into weak areas of the vertebral end-plates, or they are perceived as a common pathological pathway of different adverse and general factors such as malignancy, trauma, infection, osteoporosis, Paget's disease and so forth. A commonly accepted morphological definition of what precisely constitute SNs does not exist, and consequently prevalences vary wildly in the literature. In the present study of 4,151 standardized lateral radiographs of the lumbar spine in an adult, Caucasian population between 22 and 93 years (median age 63 years, M 1,533, W 2,618).
We investigated prevalence, distribution and epidemiologic relationships of SNs.
SNs occur primarily in the upper part of the lumbar spine, and usually there are multiple lesions in the same individual. We could not establish any significant correlation between SNs and gender, age, BMI, height, weight or occupational exposure for heavy lifting. The overall prevalence was 3.8%. We did not find any significant correlations between SNs and overall degeneration of the lumbar spine.
We found a prevalence of SNs in the lower end of the spectrum than hitherto reported.
在因不同原因而进行的正常成年人的椎体影像学检查中,经常可以看到 Schmorl 结节(SNs),放射科医生会对其进行适当的标注。然而,关于其病因知之甚少:SNs 被认为是椎间盘组织向椎体终板薄弱区域的大部分无活性的发育性或先天性疝出,或者它们被认为是不同不利和一般因素(如恶性肿瘤、创伤、感染、骨质疏松症、佩吉特病等)的常见病理途径。对于究竟什么构成了 SNs,目前还没有一个普遍接受的形态学定义,因此文献中的患病率差异很大。在本研究中,对 22 至 93 岁(中位年龄 63 岁,M 为 1533 人,W 为 2618 人)的成年白种人进行了 4151 例标准侧位腰椎 X 线片的研究。
我们研究了 SNs 的患病率、分布和流行病学关系。
SNs 主要发生在腰椎的上部,通常同一患者有多个病变。我们无法确定 SNs 与性别、年龄、BMI、身高、体重或重物搬运职业暴露之间存在任何显著相关性。总体患病率为 3.8%。我们没有发现 SNs 与腰椎整体退变之间存在任何显著相关性。
我们发现 SNs 的患病率处于此前报道的较低范围。