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超高分子量聚乙烯并不能减少全膝关节置换术后的磨损:滑液中颗粒的体内研究。

Highly crosslinked polyethylene does not reduce the wear in total knee arthroplasty: in vivo study of particles in synovial fluid.

机构信息

Department of Orthopaedic Surgery, Universitat Autònoma de Barcelona, Parc de Salut Mar. Barcelona, Spain.

出版信息

J Arthroplasty. 2013 Sep;28(8):1333-7. doi: 10.1016/j.arth.2013.01.026. Epub 2013 Mar 16.

DOI:10.1016/j.arth.2013.01.026
PMID:23507066
Abstract

The aim was to assess if the reduction in polyethylene wear with highly crosslinked polyethylene suggested by studies with knee simulators is confirmed in patients with a knee arthroplasty. The use of a conventional or a highly crosslinked polyethylene was randomly assigned intraoperatively. Twelve months after surgery a knee arthrocentesis was performed and the synovial fluid of 17 patients in each group was studied analysing the number, size and shape of the polyethylene particles by scanning electron microscope. We found no significant differences in the concentration, size or morphology of polyethylene particles between groups. The great variability in the number of particles between individuals suggests that in vivo polyethylene wear depends on many factors and probably the type of polyethylene is not the most significant.

摘要

目的在于评估膝关节模拟器研究提示的高交联聚乙烯可减少聚乙烯磨损是否在膝关节置换患者中得到证实。术中随机分配使用传统聚乙烯或高交联聚乙烯。术后 12 个月行膝关节穿刺术,对每组 17 例患者的关节滑液进行研究,通过扫描电子显微镜分析聚乙烯颗粒的数量、大小和形状。我们发现两组间聚乙烯颗粒的浓度、大小或形态无显著差异。个体间聚乙烯颗粒数量的巨大差异表明,聚乙烯的体内磨损取决于许多因素,可能聚乙烯的类型并不是最重要的因素。

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