Department of Epidemiology and Public Health, University College London Medical School, London, UK.
Psychol Med. 2013 Dec;43(12):2649-56. doi: 10.1017/S0033291713000342. Epub 2013 Mar 14.
Diagnosis of depressive disorder using interviewer-administered instruments is expensive and frequently impractical in large epidemiological surveys. The aim of this study was to assess the validity of three self-completion measures of depressive disorder and other psychiatric disorders in older people against an interviewer-administered instrument.
A random sample stratified by sex, age and social position was selected from the Whitehall II study participants. This sample was supplemented by inclusion of depressed Whitehall II participants. Depressive disorder and other mental disorders were assessed by the interviewer-administered structured revised Clinical Interview Schedule (CIS-R) in 277 participants aged 58-80 years. Participants also completed a computerized self-completion version of the CIS-R in addition to the General Health Questionnaire (GHQ) and the Center for Epidemiologic Studies Depression Scale (CES-D).
The mean total score was similar for the interviewer-administered (4.43) and self-completion (4.35) versions of the CIS-R [95% confidence interval (CI) for difference -0.31 to 0.16]. Differences were not related to sex, age, social position or presence of chronic physical illness. Sensitivity/specificity of self-completion CIS-R was 74%/98% for any mental disorder and 75%/98% for depressive episode. The corresponding figures were 86%/87% and 78%/83% for GHQ and 77%/89% and 89%/86% for CES-D.
The self-completion computerized version of the CIS-R is feasible and has good validity as a measure of any mental disorder and depression in people aged ≥ 60 years. GHQ and CES-D also have good criterion validity as measures of any mental disorder and depressive disorder respectively.
使用访谈者管理的工具来诊断抑郁症在大型流行病学调查中既昂贵又不切实际。本研究的目的是评估三种自我完成的老年人抑郁障碍和其他精神障碍的测量方法与访谈者管理的工具相比的有效性。
从 Whitehall II 研究参与者中按性别、年龄和社会地位进行分层随机抽样。通过纳入抑郁的 Whitehall II 参与者,对该样本进行了补充。在 277 名年龄在 58-80 岁的参与者中,使用访谈者管理的结构化修订版临床访谈时间表(CIS-R)评估抑郁障碍和其他精神障碍。参与者还完成了 CIS-R 的计算机化自我完成版本,以及一般健康问卷(GHQ)和中心流行病学研究抑郁量表(CES-D)。
访谈者管理的(4.43)和自我完成的(4.35)CIS-R 总分相似[差异的 95%置信区间(CI)为-0.31 至 0.16]。差异与性别、年龄、社会地位或是否存在慢性身体疾病无关。自我完成 CIS-R 的敏感性/特异性为任何精神障碍的 74%/98%和抑郁发作的 75%/98%。相应的数字分别为 GHQ 的 86%/87%和 CES-D 的 77%/89%。
CIS-R 的自我完成计算机化版本是可行的,并且在≥60 岁人群中作为任何精神障碍和抑郁症的测量方法具有良好的有效性。GHQ 和 CES-D 分别作为任何精神障碍和抑郁障碍的测量方法也具有良好的标准有效性。