Mittal Veena, Ichhpujani R L
Zoonosis Division, National Center for Disease Control, New Delhi, India.
Trop Parasitol. 2011 Jan;1(1):9-14. doi: 10.4103/2229-5070.72109.
Toxplasmosis is an important zoonotic disease caused by protozoan parasite Toxoplasma gondii. The disease affects one-third of the total world population. Transmission of the disease is mainly by ingestion of food or water contaminated with oocysts. Congenital toxoplasmosis occurs from the transplacental passage of the parasite from mother to fetus. In most adults it does not cause serious illness, but it can cause blindness and mental retardation in congenitally infected children, and it is a devastating disease in immunocompromised individuals. Diagnosis of toxoplasmosis can be established by the direct detection of the parasite or by serological methods. The most commonly used and effective therapeutic regimen is the combination of pyrimethamine with sulfadiazine and folinic acid. This article provides an overview and update on transmission, diagnosis, management, and prevention of toxoplasmosis.
弓形虫病是一种由原生动物寄生虫刚地弓形虫引起的重要人畜共患病。该疾病影响着全球三分之一的人口。疾病的传播主要通过摄入被卵囊污染的食物或水。先天性弓形虫病是由于寄生虫经胎盘从母亲传播给胎儿所致。在大多数成年人中，它不会引起严重疾病，但在先天性感染的儿童中，它可导致失明和智力发育迟缓，并且在免疫功能低下的个体中是一种毁灭性疾病。弓形虫病的诊断可通过直接检测寄生虫或血清学方法来确定。最常用且有效的治疗方案是乙胺嘧啶与磺胺嘧啶及亚叶酸联合使用。本文提供了关于弓形虫病的传播、诊断、管理和预防的概述及最新信息。
