Infectious Diseases Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Spain.
Curr Opin Pulm Med. 2013 Jul;19(4):350-6. doi: 10.1097/MCP.0b013e3283606ab5.
The aim of this review is to highlight recent changes concerning the incidence of empyema. In this article we have focused on community-acquired empyema
The incidence of empyema seems to have been increasing both in children and adults worldwide in the past decades, mainly in healthy young adults and in older patients. The bacteriology of pleural infection is changing as well. In children, the most common microorganism that causes empyema continues to be Streptococcus pneumoniae. Interestingly, the widespread use of the seven valent conjugate vaccine has produced a replacement phenomenon with the emergence of some pneumococcal serotypes such as serotypes 1, 3 and 19A, which have a higher propensity to cause empyema. Moreover increases in the incidence of empyema due to Staphylococcus aureus have also been observed. In adults, increases in the rate of empyema due to Streptococcus milleri group and S. aureus have been reported.
Continued surveillance in the epidemiology of empyema is needed. Progress in new strategies of prevention, such as a new generation of conjugate pneumococcal vaccines and protein-based vaccines, could become an important step in the control of this important complication.
目的综述: 本篇综述的目的是强调近年来有关脓胸发病率的变化。本文重点关注社区获得性脓胸。
最近发现: 在过去几十年中,全球范围内儿童和成人的脓胸发病率似乎都在增加,主要发生在健康的年轻成年人和老年患者中。胸腔感染的细菌学也在发生变化。在儿童中,导致脓胸的最常见微生物仍然是肺炎链球菌。有趣的是,由于 7 价结合疫苗的广泛使用,一些肺炎球菌血清型(如 1、3 和 19A 型)的出现导致了替代现象,这些血清型更容易引起脓胸。此外,由于金黄色葡萄球菌引起的脓胸发病率也有所增加。在成年人中,由于米勒链球菌和金黄色葡萄球菌引起的脓胸发生率也有所增加。
总结: 需要对脓胸的流行病学进行持续监测。在预防策略方面取得进展,例如新一代结合肺炎球菌疫苗和基于蛋白质的疫苗,可能成为控制这一重要并发症的重要一步。