Kirchhof Mark G, de Gannes Gillian C
Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada.
Skin Therapy Lett. 2013 Feb;18(2):5-7.
Parabens are preservatives used in a variety of personal care, cosmetic, pharmaceutical and food products. Studies have confirmed the ubiquitous presence of parabens, with levels detected in wastewater, rivers, soil and house dust. Parabens have also been detected in human tissues and bodily fluids, but it is the discovery of these chemical compounds in the breast tissue of patients with breast cancer that has raised public concern over their use. It is hypothesized that the estrogenic properties of parabens may play a role in breast cancer development. However, studies investigating the health effects of parabens are conflicting. At this point, there is an insufficient amount of data suggesting serious consequences from paraben use and exposure to warrant drastic avoidance measures or government regulations.
对羟基苯甲酸酯是用于各种个人护理、化妆品、药品和食品中的防腐剂。研究已证实对羟基苯甲酸酯广泛存在,在废水、河流、土壤和室内灰尘中均检测到其含量。在人体组织和体液中也检测到了对羟基苯甲酸酯,但正是在乳腺癌患者的乳腺组织中发现了这些化合物,才引起了公众对其使用的关注。据推测,对羟基苯甲酸酯的雌激素特性可能在乳腺癌发展中起作用。然而,关于对羟基苯甲酸酯对健康影响的研究结果相互矛盾。目前,没有足够的数据表明使用和接触对羟基苯甲酸酯会产生严重后果,从而有必要采取严厉的避免措施或政府监管。