Takahashi S, Hirano Y, Kawamura T, Homma Y
Department of Urology, The Fraternity Memorial Hospital.
Int J STD AIDS. 2013 Jan;24(1):67-9. doi: 10.1258/ijsa.2012.012167. Epub 2013 May 6.
A 33-year-old man was referred to our institution with papillary masses at the urethral meatus and difficulty urinating. Genital examination showed two piercings on the frenulum, which were penetrating the external urethra. Endoscopic examination revealed papillary tumours over the entire circumference of the penile urethra and the piercing site. The tumours were resected transurethrally. Microscopic examination revealed condylomata acuminata. Human papillomavirus types 6 and 66 were detected in the lesions. Retrograde urethral viral infection is rare because of the protection provided by the mucosal immune system. Genital piercing may have facilitated spread of the human papillomavirus into the urethra.
一名33岁男性因尿道口乳头状肿物及排尿困难转诊至我院。生殖器检查发现系带处有两处穿孔，已穿透尿道外口。内镜检查显示阴茎尿道及穿孔部位全周均有乳头状肿瘤。经尿道切除肿瘤。显微镜检查显示为尖锐湿疣。在病变中检测到6型和66型人乳头瘤病毒。由于黏膜免疫系统的保护，逆行性尿道病毒感染较为罕见。生殖器穿孔可能促使了人乳头瘤病毒向尿道扩散。
