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髋关节置换术后的全身性疾病:人工关节钴中毒的航空医学影响

Systemic disease after hip replacement: aeromedical implications of arthroprosthetic cobaltism.

作者信息

Sotos John G, Tower Stephen S

机构信息

Joint Forces Headquarters, California Air National Guard, 9800 Goethe Road, Box 15, Sacramento, CA 95827, USA.

出版信息

Aviat Space Environ Med. 2013 Mar;84(3):242-5. doi: 10.3357/asem.3262.2013.

DOI:10.3357/asem.3262.2013
PMID:23513286
Abstract

BACKGROUND

A multisystem illness recently reported in recipients of the newest generation of metal-on-metal hip prostheses has been ascribed to toxic effects of cobalt and possibly chromium.

CASE REPORT

We present a case of insidiously developing neurologic illness that occurred in a physically active professional.

DISCUSSION

This case illustrates the potential for a hip prosthesis to occultly impair safe functioning of aviators. Based on this case and others, we suggest modifications to aeromedical policy relating to waiver requests after hip replacement, including routine monitoring of serum cobalt and chromium levels in recipients of metal-on-metal hip prostheses. The evaluation of aviators having an elevated cobalt level is also discussed.

摘要

背景

最近在接受最新一代金属对金属髋关节假体的患者中报告了一种多系统疾病,该疾病被归因于钴以及可能的铬的毒性作用。

病例报告

我们呈现了一例发生在一名身体活跃的专业人员身上的隐匿性发展的神经系统疾病病例。

讨论

该病例说明了髋关节假体可能会隐匿性地损害飞行员的安全功能。基于此病例及其他病例,我们建议对髋关节置换术后豁免请求的航空医学政策进行修改,包括对接受金属对金属髋关节假体的患者进行血清钴和铬水平的常规监测。还讨论了对钴水平升高的飞行员的评估。

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