Durand Dante, Delgado Leticia L, de la Parra-Pellot Dhizarah Matus, Nichols-Vinueza Diana
University of Miami Miller School of Medicine, Miami, FL.
Universidad del Valle, Cali, Colombia.
Clin Schizophr Relat Psychoses. 2015 Jan;8(4):205-8. doi: 10.3371/CSRP.DUDE.031513.
Synthetic cannabinoid (SC) or "spice" refers to a variety of herbal/chemical mixtures, which mimic the effects of marijuana. They are generally marked as "herbal incense" and best known by the brand names of "K2," "spice," "aroma," "Mr. Nice Guy" and "dream." Little data are available on the psychopathological and physical effects of SC.
We reported on a 23-year-old man without prior psychiatric history who developed acute psychosis and severe rhabdomyolysis (creatine phosphokinase [CPK]: 44,300 UI/L) associated with "Mr. Nice Guy" consumption. To our knowledge, this is the first case report of severe rhabdomyolysis associated with SC use in the U.S.
Physicians should be aware of the possibility of new-onset psychotic symptoms and rhabdomyolysis in patients that use SC.
合成大麻素（SC）或“香料”指的是多种模仿大麻效果的草药/化学混合物。它们通常被标记为“草药香料”，最知名的品牌有“K2”、“香料”、“香气”、“好好先生”和“梦境”。关于合成大麻素的精神病理学和身体影响的数据很少。
我们报告了一名23岁无前科病史的男性，他在吸食“好好先生”后出现急性精神病和严重横纹肌溶解（肌酸磷酸激酶[CPK]：44300 UI/L）。据我们所知，这是美国首例与使用合成大麻素相关的严重横纹肌溶解病例报告。
医生应意识到使用合成大麻素的患者出现新发精神病症状和横纹肌溶解的可能性。
