Southmead Hospital, North Bristol NHS Trust, Bristol, UK.
Curr Opin Crit Care. 2013 Jun;19(3):181-7. doi: 10.1097/MCC.0b013e328360ac5e.
The optimal method for airway management during cardiac arrest is unknown. This review summarizes recent evidence comparing the use of basic and advanced airway interventions [insertion of supraglottic airway (SGA) devices and tracheal intubation], including the role of capnography during cardiac arrest.
A large observational study [649,359 out-of-hospital cardiac arrests (OHCAs)] has shown that the risk-adjusted odds of neurologically favourable survival were higher for those treated with bag-mask ventilation compared with SGA insertion or tracheal intubation. Two recent, large observational studies suggest that tracheal intubation for OHCA may be superior to SGA use. These observational studies share an important weakness: they rely on statistical risk-adjustment to account for other factors that may influence outcome, and hidden confounders may account for the differences in outcome associated with each of the airway management strategies.
Most of the evidence about airway management during cardiac arrest comes from observational studies. The best airway option is likely to be different for different rescuers, and at different time points of the resuscitation process. Properly designed, prospective, randomized trials are needed to help determine the optimal airway strategy. In our view, there is currently sufficient clinical equipoise to support such trials.
心脏骤停期间气道管理的最佳方法尚不清楚。本综述总结了最近比较基本和高级气道干预措施(包括使用声门上气道装置和气管插管)的使用的证据,包括心脏骤停期间二氧化碳描记术的作用。
一项大型观察性研究(649359 例院外心脏骤停(OHCA))表明,与 SGA 插入或气管插管相比,接受球囊面罩通气治疗的患者,其神经功能良好生存的风险调整优势比更高。最近的两项大型观察性研究表明,对于 OHCA,气管插管可能优于 SGA 应用。这些观察性研究有一个共同的重要弱点:它们依赖于统计学上的风险调整来解释可能影响结果的其他因素,而隐藏的混杂因素可能解释了与每种气道管理策略相关的结果差异。
心脏骤停期间气道管理的大部分证据来自观察性研究。对于不同的抢救者,以及在复苏过程的不同时间点,最佳的气道选择可能不同。需要设计合理、前瞻性、随机试验来帮助确定最佳的气道策略。在我们看来,目前有足够的临床平衡来支持这些试验。