Matta Noelle, Silbert David I
Binocul Vis Strabolog Q Simms Romano. 2013;28(1):39-44.
We set out to determine the accommodative effects of Atropine on the visual system.
A prospective study was done on a normal eye in a 31-year-old cooperative adult. One drop of 1% Atropine was instilled and the effect on accommodation, near visual acuity and pupil size was recorded. Accommodation was measured at 1/3 of a meter utilizing the Grand Seiko Auto Refractor. Near visual acuity was measured with the PEDIG ATS 4 near visual acuity test at a set distance of 16 inches.
Atropine caused its greatest effect to accommodation, and to pupil size, 3 hours after installation. Curiously, the greatest effect on near visual acuity was seen 27 hours after instillation at which time it dropped to 20/80. Near visual acuity had improved to 20/25 on day 4. Accommodation returned to normal 8 days after instillation and pupil size returned to normal 12 days after instillation.
One drop of Atropine affected accommodation for 8 days. Despite this, near vision returned to 20/20 by day 5. These findings may impact how Atropine penalization is prescribed to treat amblyopia both to maximize effectiveness and minimize its impact on school performance.
我们着手确定阿托品对视觉系统的调节作用。
对一名31岁配合良好的成年人的一只正常眼睛进行了一项前瞻性研究。滴入一滴1%的阿托品，并记录其对调节、近视力和瞳孔大小的影响。使用精工自动验光仪在1/3米处测量调节。使用PEDIG ATS 4近视力测试在16英寸的固定距离测量近视力。
阿托品在滴入后3小时对调节和瞳孔大小产生最大影响。奇怪的是，滴入后27小时对近视力的影响最大，此时近视力降至20/80。第4天近视力提高到20/25。滴入后8天调节恢复正常，滴入后12天瞳孔大小恢复正常。
一滴阿托品影响调节8天。尽管如此，到第5天近视力恢复到20/20。这些发现可能会影响阿托品压抑疗法治疗弱视的处方方式，以最大限度地提高疗效并最小化其对学习成绩的影响。
