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罗克福汀在青霉菌种中的合成与代谢

Synthesis and metabolism of roquefortine in Penicillium species.

作者信息

Reshetilova T A, Kozlovsky A G

机构信息

Institute of Biochemistry and Physiology of Microorganisms, USSR Academy of Sciences, Pushichino, Moscow Region.

出版信息

J Basic Microbiol. 1990;30(2):109-14. doi: 10.1002/jobm.3620300213.

DOI:10.1002/jobm.3620300213
PMID:2352134
Abstract

The uptake of exogeneous 14C-roquefortine by Penicillium farinosum cells and its metabolism was followed. Growth and roquefortine biosynthesis of three Penicillium species during a cultivation period of 14 d were investigated. Furthermore, the effect of cultivation conditions viz. various culture media on roquefortine uptake and biosynthesis as well as biomass production were studied. Some general problems of physiology and metabolic regulation of alkaloid formation in Penicillium species were discussed.

摘要

研究了粉状青霉细胞对外源14C-棒曲霉素的摄取及其代谢情况。对三种青霉在14天培养期内的生长及棒曲霉素生物合成进行了研究。此外,还研究了培养条件,即各种培养基对棒曲霉素摄取、生物合成以及生物量产生的影响。讨论了青霉属生物碱形成过程中的一些生理学和代谢调节的一般问题。

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1
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2
[Factors contributing to roquefortine yield variability during cultivation of penicillium roquefortii].
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引用本文的文献

1
Roquefortine/oxaline biosynthesis pathway metabolites in Penicillium ser. Corymbifera: in planta production and implications for competitive fitness.匐枝青霉中罗克福汀/草氨酸生物合成途径代谢产物:植物体内的产生及其对竞争适应性的影响
J Chem Ecol. 2005 Oct;31(10):2373-90. doi: 10.1007/s10886-005-7107-y. Epub 2005 Sep 28.