Rothman Institute at Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
J Arthroplasty. 2013 Jun;28(6):904-7. doi: 10.1016/j.arth.2012.12.018. Epub 2013 Mar 21.
Metabolic syndrome (MetS)-a diagnostic grouping of diabetes, dyslipidemia, hypertension, and obesity-has been indicated as a risk factor for perioperative complications following total joint arthroplasty (TJA). This study investigates the impact of MetS on perioperative complications, specifically the importance of controlling MetS components. One hundred thirty-three patients undergoing TJA with all four components of MetS were identified. They were matched one-to-one with patients without MetS. Control of diabetes, dyslipidemia, and hypertension was assessed. Thirty-five patients with MetS were found to have at least a single uncontrolled component. The complication rates were 49%, 8%, and 8% for uncontrolled MetS, controlled MetS, and no MetS, respectively. Multivariate analysis confirmed independent associations between control of MetS components and both perioperative complications and length of stay. Both surgeons and patients should be aware of the substantial risk of dangerous complications following TJA in patients with uncontrolled metabolic syndrome.
代谢综合征（MetS）——一种糖尿病、血脂异常、高血压和肥胖症的诊断分组——已被指出是全关节置换术（TJA）后围手术期并发症的危险因素。本研究调查了 MetS 对围手术期并发症的影响，特别是控制 MetS 成分的重要性。确定了 133 例接受 TJA 且 MetS 具有所有四个成分的患者。他们与没有 MetS 的患者一一匹配。评估了糖尿病、血脂异常和高血压的控制情况。发现 35 例 MetS 患者至少有一个未控制的成分。未控制的 MetS、控制的 MetS 和没有 MetS 的并发症发生率分别为 49%、8%和 8%。多变量分析证实了 MetS 成分控制与围手术期并发症和住院时间之间的独立关联。外科医生和患者都应该意识到，在未控制的代谢综合征患者中，TJA 后存在严重并发症的风险。
